81127-07-3

Basic information

• Product Name: 11β,17β-dihydroxy-21-(2-phenyl-ethyl)-17α-pregn-4-en-20-yn-3-one
• CAS NO: 81127-07-3
• Molecular Weight: 432.603
• Mol File: 81127-07-3.mol

Chemical Properties

• CAS DataBase Reference: 11β,17β-dihydroxy-21-(2-phenyl-ethyl)-17α-pregn-4-en-20-yn-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 11β,17β-dihydroxy-21-(2-phenyl-ethyl)-17α-pregn-4-en-20-yn-3-one(81127-07-3)
• EPA Substance Registry System: 11β,17β-dihydroxy-21-(2-phenyl-ethyl)-17α-pregn-4-en-20-yn-3-one(81127-07-3)

Safety Data

• Hazardous Substances Data: 81127-07-3(Hazardous Substances Data)

Upstream product

• 16520-62-0 4-Phenyl-1-butyne 
• 54668-65-4 3-ethoxy-11β-hydroxy-3,5-androstadien-17-one 

Relevant articles and documents

17α-Alkynyl-11β,17-dihydroxyandrostane derivatives: A new class of potent glucocorticoids

Replacement of the characteristic dihydroxyacetone side chain of corticoids by a 17α-alkynyl-17β-hydroxy moiety was investigated.It was found that, in particular, the 17α-propynyl substitution is favorable for high local anti-inflammatory activity with reduced systemic effects.Moreover, these compounds were found to be devoid of any affinity for the aldosterone receptor, and may thus be considered as pure glucocorticoids.