81128-31-6

Basic information

• Product Name: Cyclohexyl-quinolin-4-yl-methanone
• CAS NO: 81128-31-6
• Molecular Weight: 239.317
• Mol File: 81128-31-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Cyclohexyl-quinolin-4-yl-methanone(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexyl-quinolin-4-yl-methanone(81128-31-6)
• EPA Substance Registry System: Cyclohexyl-quinolin-4-yl-methanone(81128-31-6)

Safety Data

• Hazardous Substances Data: 81128-31-6(Hazardous Substances Data)

Upstream product

• 79476-06-5 4-trimethylstannyl-quinoline 
• 2719-27-9 cyclohexanylcarbonyl chloride 

Relevant articles and documents

Studies on Organometallic Compounds. III. Reaction of Trimethylstannylazines with Acyl Chlorides. A Novel C-C Bond Formation of Pyridine Nuclei

Introduction of an acyl group at the α-, β-, and γ-positions of pyridine nuclei was accomplished. 2-Trimethylstannyl-pyridine and -quinoline and 1-trimethylstannylisoquinoline directly reacted with various acyl chlorides to give the corresponding 2-pyridyl, 2-quinolyl, and 1-isoquinolyl ketones, respectively.Reaction of 3-trimethylstannylpyridine, -quinoline, and -isoquinoline with acyl chlorides proceeded smoothly under catalysis by PdCl2 or PdCl2(PPh3)2 to afford the corresponding ketones in good yields.Similary, 4-pyridyl, -quinolyl, and -isoquinolyl ketones were prepared from corresponding 4-trimethylstannyl derivatives and acyl chlorides.Keywords--trimethylstannylazine; palladium-catalyzed reaction; acylation; palladium dichloride; dichlorobis(triphenylphosphine)palladium(II)