81135-30-0Relevant academic research and scientific papers
Synthesis of D-lysine8-cyclosporine A. Further characterization of BOP-C1 in the 2-7 hexapeptide fragment synthesis
Colucci,Tung,Petri,Rich
, p. 2895 - 2903 (2007/10/02)
The coupling reagent N,N-bis(2-oxo-3-oxazolidinyl)phosphinic chloride (BOP-Cl) has been used to synthesize the 2-7 hexapeptide fragment of cyclosporine A. The reagent proved useful in four of the five coupling steps with yields ranging from 78 to 92%. Ove
Synthesis and Antimitogenic Activities of Four Analogues of Cyclosporin A Modified in the 1-Position
Rich, Daniel H.,Dhaon, Madhup K.,Dunlap, Brian,Miller, Stephen P. F.
, p. 978 - 984 (2007/10/02)
Cyclosporin A (CSA,1), an immunosuppressive cyclic undecapeptide, contains a unique N-methylated amino acid, (2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(N-methylamino)-6-octenoic acid, called both C-9-ene and MeBmt that
