81139-01-7

Basic information

• Product Name: 2-(4-Chloro-phenyl)-7,7-diethyl-imidazo[1',2':4,5][1,3,4]thiadiazolo[3,2-a]pyrimidine-6,8-dione
• CAS NO: 81139-01-7
• Molecular Weight: 374.851
• Mol File: 81139-01-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(4-Chloro-phenyl)-7,7-diethyl-imidazo[1',2':4,5][1,3,4]thiadiazolo[3,2-a]pyrimidine-6,8-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-Chloro-phenyl)-7,7-diethyl-imidazo[1',2':4,5][1,3,4]thiadiazolo[3,2-a]pyrimidine-6,8-dione(81139-01-7)
• EPA Substance Registry System: 2-(4-Chloro-phenyl)-7,7-diethyl-imidazo[1',2':4,5][1,3,4]thiadiazolo[3,2-a]pyrimidine-6,8-dione(81139-01-7)

Safety Data

• Hazardous Substances Data: 81139-01-7(Hazardous Substances Data)

Upstream product

• 16163-53-4 2-Amino-6-(4-chlorphenyl)-imidazo(2,1-b)-1,3,4-thiadiazol 
• 77-25-8 diethyl diethylmalonate 

Relevant articles and documents

Reactions of 2-Aminoimidazo-1,3,4-thiadiazoles with Ethyl Dicarboxylates in Polyphosphoric Acid (PPA)

The 2-amino-6-arylimidazo-1,3,4-thiadiazoles 1d,e cyclise on heating in polyphosphoric acid (PPA) with ethyl malonate or ethyl diethylmalonate to yield the 2-aryl-6,8-dioxodihydro-6H-imidazo-1,3,4-thiazolo pyrimidines 3d,e or the 7,7-diethyl compounds 4d,e.Compounds 1a-f cyclise in PPA with ethyl succinate or ethyl phthalate to yield the 6-aryl-2-succinimido- or 6-aryl-2-phthalimido-imidazo-1,3,4-thiadiazoles 5a, b, d-f and 6a-f.Compounds 1d,e were condensed with ethyl oxalate to yield the 2-(ethoxycarbonyl-formylamino)-6-arylimidazo-1,3,4-thiadiazoles 7d,e.Ethyl levulinate with 1d,e in PPA probably forms 6-aryl-2-(2-methyl-5-oxo-Δ3-pyrrolino)imidazo-1,3,4-thiadiazoles.