811419-63-3

Upstream product

• 1202-04-6 indole-2-carboxylic acid methyl ester 
• 160309-18-2 (1R,4R,5S,6R)-4,5-(isopropylidenedioxy)-7-(4'-methylphenylsulfonyl)-7-azabicyclo<4.1.0>hept-2-ene 

Downstream Products

• 811419-68-8 C₃₆H₄₄N₂O₁₁S 
• 811419-67-7 3-[(1aR,2R,3R,3aS,6aS,6bR)-5,5-Dimethyl-3-(toluene-4-sulfonylamino)-hexahydro-1,4,6-trioxa-cyclopropa[e]inden-2-yl]-1H-indole-2-carboxylic acid methyl ester 
• 811419-65-5 N-((3aS,4S,4aR,11cR,12R,12aS)-4-Iodo-2,2-dimethyl-6-oxo-3a,4,4a,6,7,11c,12,12a-octahydro-1,3,5-trioxa-7-aza-indeno[5,6-c]fluoren-12-yl)-4-methyl-benzenesulfonamide 
• 811419-64-4 3-[(3aS,4R,5R,7aR)-2,2-Dimethyl-4-(toluene-4-sulfonylamino)-3a,4,5,7a-tetrahydro-benzo[1,3]dioxol-5-yl]-1H-indole-2-carboxylic acid 

Relevant academic research and scientific papers

A β-carboline-1-one mimic of the anticancer Amaryllidaceae constituent pancratistatin: Synthesis and biological evaluation

New drug design possibilities are suggested by the results of a biological evaluation of the indole derivative 1 of pancratistatin, a known anticancer agent, in a panel of cancer cell lines. Enzymatic dihydroxylation was one of the key steps in the short,

Reactions of indole derivatives with oxiranes and aziridines on silica. Synthesis of β-carbolin-1-one mimic of pancratistatin

(Chemical Equation Presented) Indole and several indoles functionalized at C-2 were condensed with oxiranes, vinyloxiranes, aziridines, and vinylaziridines in the solid state on the surface of silica. The yields of these reactions were compared to those o