81161-40-2

Upstream product

• 95-47-6 o-xylene 
• 39644-80-9 β-(4-bromobenzoyl)acrylic acid 
• 81161-39-9 β-(4-bromobenzoyl)-α-(3,4-xylyl)propionic acid 

Downstream Products

• 81153-92-6 4-(3',4'-dimethylphenyl)-6-(4''-bromophenyl)-4,5-dihydropyridazin-3-one 
• 81153-88-0 3-(4'-bromophenyl)-6-chlor-5-(3,4-xylyl)-4,5-dihydropyridazin 
• 81153-82-4 6-(4'-bromophenyl)-4-(3,4-xylyl)-2,3,4,5-tetrahydropyridazin-3-thione 
• 81153-87-9 [6-(4-Bromo-phenyl)-4-(3,4-dimethyl-phenyl)-4,5-dihydro-pyridazin-3-yloxy]-acetic acid ethyl ester 
• 81153-86-8 6-(4-bromophenyl)-4-(3,4-dimethylphenyl)-2-ethoxycarbonylmethyl-2,3,4,5-tetrahydropyridazin-3(2H)-one 
• 81153-84-6 6-(4'-bromophenyl)-2-methyl-4-(3,4-xylyl)-2,3,4,5-tetrahydropyridazin-3-one 
• 81161-41-3 6-(4'-bromophenyl)-3-methoxy-4-(3,4-xylyl)-4,5-dihydropyridazin 
• 81153-90-4 6-(4-Bromo-phenyl)-4-(3,4-dimethyl-phenyl)-3-(4-methoxy-phenyl)-4,5-dihydro-pyridazine 
• 81153-91-5 6-(4-Bromo-phenyl)-4-(3,4-dimethyl-phenyl)-3-(2-methoxy-phenyl)-4,5-dihydro-pyridazine 

Relevant academic research and scientific papers

Facile synthesis of 3(2H)-pyridazinones and 2(3H)-furanones of anticipated biological activities

3-Aroyl-2-arylpropionic acids 2a-e were utilized to synthesize 3(2H)-pyridazinones 3a-e and 2(3H)-furanones 6 through reaction with hydrazine hydrate and freshly distilled acetic anhydride, respectively, in the hope of obtaining new 3(2H)-pyridazinones wi

Synthesis and Reactions of Some α-Aryl-β-(4-bromobenzoyl)-propionic acids

Alkylation of o-xylene or p-xylene with β-(4-bromobenzoyl)acrylic acid (I) gives the corresponding propionic acid derivatives (IIa and b).The acids (II) on reaction with hydrazine hydrate yield pyridazinones (III).The reactions of III with phosphorus pent