811805-10-4Relevant articles and documents
Synthesis and antimalarial activity of 6-cycloalkylvinyl substituted 1,2,4-trioxanes
Singh, Chandan,Srivastav, Naveen Chandra,Puri, Sunil K.
, p. 5745 - 5752 (2007/10/03)
6-Cycloalkylvinyl substituted 1,2,4-trioxanes 6-15 have been prepared and tested against multi-drug resistant Plasmodium yoelii in mice. The most active trioxane 11 provides 80% protection to the treated mice. Further derivatization of 11 leads to decreas