81202-00-8 Usage
Uses
Used in Metabolic Studies:
L-GLUTAMIC ACID (5-13C) is used as a research tool for metabolic studies, enabling scientists to trace the fate of specific carbon atoms in biological systems. The stable isotope labeling allows for the tracking of metabolic pathways and the investigation of the role of L-glutamic acid in various biochemical processes.
Used in Kinetic Experiments:
In kinetic experiments, L-GLUTAMIC ACID (5-13C) serves as a valuable tracer to study the rates of enzymatic reactions and the dynamics of metabolic processes. The incorporation of the stable isotope carbon-13 allows for the accurate measurement of reaction rates and the elucidation of reaction mechanisms.
Used in Neurotransmission Research:
L-GLUTAMIC ACID (5-13C) is used as a research compound in neurotransmission studies, as it is a primary excitatory neurotransmitter in the central nervous system. The stable isotope labeling enables researchers to investigate the role of L-glutamic acid in synaptic transmission, neuronal signaling, and the regulation of cognitive functions.
Used in Energy Production Research:
L-GLUTAMIC ACID (5-13C) is utilized in research focused on energy production, as it plays a crucial role in the tricarboxylic acid (TCA) cycle and the generation of ATP. The stable isotope labeling allows for the tracking of carbon atoms through the metabolic pathways involved in energy production, providing insights into the regulation and efficiency of these processes.
Used in Pharmaceutical and Diagnostic Development:
L-GLUTAMIC ACID (5-13C) is employed in the development of pharmaceuticals and diagnostic tools, as its stable isotope labeling can be used to study the interactions of L-glutamic acid with various drugs, enzymes, and receptors. This information can be valuable for the design of targeted therapies and the development of diagnostic assays for monitoring L-glutamic acid levels in biological samples.
Used in Nutritional Research:
In nutritional research, L-GLUTAMIC ACID (5-13C) is used to study the role of L-glutamic acid in dietary intake and its impact on health and disease. The stable isotope labeling allows for the investigation of the bioavailability, absorption, and metabolism of L-glutamic acid from various food sources, contributing to a better understanding of its nutritional importance.
Used in Environmental and Ecological Studies:
L-GLUTAMIC ACID (5-13C) is utilized in environmental and ecological studies to investigate the role of L-glutamic acid in the nitrogen cycle and its interactions with other organisms and ecosystems. The stable isotope labeling enables researchers to track the movement and transformation of L-glutamic acid in various environmental settings, providing insights into its ecological significance.
Check Digit Verification of cas no
The CAS Registry Mumber 81202-00-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,2,0 and 2 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 81202-00:
(7*8)+(6*1)+(5*2)+(4*0)+(3*2)+(2*0)+(1*0)=78
78 % 10 = 8
So 81202-00-8 is a valid CAS Registry Number.
81202-00-8Relevant academic research and scientific papers
Carbapenem biosynthesis: Confirmation of stereochemical assignments and the role of CarC in the ring stereoinversion process from L-Proline
Stapon, Anthony,Li, Rongfeng,Townsend, Craig A.
, p. 8486 - 8493 (2007/10/03)
(5R)-Carbapen-2-em-3-carboxylic acid is the simplest structurally among the naturally occurring carbapenem β-lactam antibiotics. It co-occurs with two saturated (3S,5S)- and (3S,5R)-carbapenam carboxylic acids. Confusion persists in the literature about t
Chemo-enzymatic synthesis of specifically stable-isotope labelled L-glutamic acid and 2-oxoglutaric acid
Cappon, J. J.,Baart, J.,Walle, G. A. M. van der,Raap, J.,Lugtenburg, J.
, p. 158 - 166 (2007/10/02)
(3-13C)-(4-13C)-,(5-13C)- and (3,4-13C2)-2-oxoglutaric acid were prepared starting from the simple 13C-enriched compounds: ethyl bromoacetate and paraformaldehyde, via a single reaction scheme on the gram scale in high yield.This reaction scheme allows specific 13C enrichment of every carbon position and any combination of positions. (3-13C)-,(4-13C)-, (5-13C), (3,4-13C2) and (15N)-L-glutamic acid were prepared by converting the corresponding 2-oxoglutaric acids via an enantioselective enzymatic conversion.The labelled L-glutamic acids and 2-oxoglutaric acids were characterized by 1H NMR, 13C NMR and mass spectrometry.
