81224-34-2

Usage

Uses

Used in Organic Synthesis:
2-(3-bromo-4-methoxyphenyl)-2-methyl-1,3-dioxolane is used as a building block for the synthesis of various organic compounds. Its unique structural features, including the bromine atom and methoxy group, allow for versatile reactions and the formation of a wide range of products.
Used in Pharmaceutical Research:
2-(3-bromo-4-methoxyphenyl)-2-methyl-1,3-dioxolane is used as an intermediate in the synthesis of pharmaceuticals. Its potential biological activities and reactivity make it a valuable component in the development of new drugs and therapeutic agents.
Used in Agrochemicals:
2-(3-bromo-4-methoxyphenyl)-2-methyl-1,3-dioxolane is used as an intermediate in the synthesis of agrochemicals. Its properties and reactivity contribute to the development of effective and efficient agricultural products, such as pesticides and herbicides.
Used in Chemical Research:
2-(3-bromo-4-methoxyphenyl)-2-methyl-1,3-dioxolane is used as a research compound in the field of chemistry. Its unique properties and reactivity provide opportunities for studying various chemical reactions and processes, contributing to the advancement of chemical knowledge and technology.

Upstream product

• 578-57-4 2-bromoanisole 
• 35310-75-9 3-bromo-4-methoxyacetophenone 
• 107-21-1 ethylene glycol 

Downstream Products

• 1215281-20-1 5-acetyl-2-methoxyboronic acid 
• 81224-38-6 methoxy-4 acetyl-7 indole 
• 531-99-7 5-acetyl-2-methoxybenzaldehyde 
• 81224-35-3 dioxolanne de l'acetyl-3 methoxy-6 benzaldehyde 

Relevant academic research and scientific papers

A boronic acid chalcone analog of combretastatin A-4 as a potent anti-proliferation agent

Chalcones represent a class of natural products that inhibits tubulin assembly. In this study we designed and synthesized boronic acid analogs of chalcones in an effort to compare biological activities with combretastatin A-4, a potent inhibitor of tubuli

Substituent Control of Intramolecular Hydrogen Bonding in Formyl-Protonated o-Anisaldehydes: A Stable Ion and Semiempirical MO Investigation

o-Anisaldehyde and its 5-Br, 5-F, 5-CF3, 5-CN, 5-NO2, and 5-COMe derivatives are protonated at the formyl group in 1 : 1 SbF5-FSO3H/SO2 (or SO2ClF) to give persistent carboxonium ions as mixtures of Z and E geometrical isomers.The cyano, nitro, and acetyl substituents are also protonated, leading to dications and additional geometrical isomers in the nitro and acetyl cases.The carboxonium ions are predominantly in the Z,syn configuration, but with increased amounts of the E,anti configuration with increased electron withdrawal by the substituents.With 5-NO2H(+), Eisomers become more abundant than Z.The formyl protonated 2-(trifluoromethoxy)benzaldehyde shows a strong preference for the E configuration.The preference for the Z,syn form is attributed to intramolecular hydrogen bonding that becomes less favorable as electron density is withdrawn from the methoxyl oxygen.The log Z/E values correlate with differences in energy content of the isomers predicted in AM1 calculations, and the chemical shift of the hydroxyl proton of the carboxonium group correlates well with predicted charge on the proton.

Synthese de derives indoliques substitues in 7

The synthesis and some aspects of the chemical reactivity of 7-acetyl, 7-benzoyl and 7-bromoindoles are described.