81233-50-3Relevant academic research and scientific papers
Efficient synthesis of 2-aminothiazole-4-phenyl-5-acetamides via the open chain tautomers of γ-keto amides
Tsolomiti, Georgia,Tsolomitis, Athanase
, p. 501 - 507 (2007/10/03)
A simple and efficient method is described for the synthesis of new functionalized 2-aminothiazoles, the 2-aminothiazole-4-phenyl-5-acetamides 5, in 67-96% yields based on an application of the Hantzsch synthesis. The method involves the reaction of thiou
Zinc carbenoid-mediated chain extension of β-keto amides
Hilgenkamp, Ramona,Zercher, Charles K
, p. 8793 - 8800 (2007/10/03)
The reaction of β-keto amides with ethyl(iodomethyl)zinc provides access to a wide variety of γ-keto amides, including primary, secondary, and tertiary amides. Although the reaction of α-substituted β-keto amides are in many cases unsatisfactory, the method can be applied to a broad spectrum of substrates that possess imide and olefinic functionality.
N,N-Dialkylamides of 2-Hydroxy-2-phenyl-cyclopropan-1-carboxylic Acid - Photochemical Synthesis and Determination of the Structure
Henning, H.-G.,Berlinghoff, R.,Mahlow, A.,Koeppel, H.,Schleinitz, K.-D.
, p. 914 - 918 (2007/10/02)
Irradiation of N,N-dialkylamides of β-benzoylpropionic acid 2a, b in ether by n,?*-excitation leads to the corresponding amides of the hitherto unknown 2-hydroxy-2-phenyl-cyclopropancarboxylic acid 3a, b, 4a, b.The photocyclization yields diast
