81238-67-7

Upstream product

• 6786-21-6 6,7-dioxabicyclo[3.2.2]nona-8-ene 
• 6786-21-6 6,7-dioxabicyclo[3.2.2]non-8-ene 

Downstream Products

• 103897-29-6 Benzoic acid (1R,7R)-7-methyl-4-oxo-cyclohept-2-enyl ester 
• 105427-85-8 Benzoic acid (1R,4S,7R)-4-methoxymethoxy-7-methyl-cyclohept-2-enyl ester 
• 103897-30-9 Benzoic acid (1R,5S,7R)-5,7-dimethyl-4-oxo-cyclohept-2-enyl ester 
• 103897-30-9 Benzoic acid (1R,5R,7R)-5,7-dimethyl-4-oxo-cyclohept-2-enyl ester 
• 1311294-63-9 benzoic acid 8-oxabicyclo[3.2.1]oct-3-en-2-yl ester 

Relevant academic research and scientific papers

PALLADIUM(0) CATALYZED REACTIONS OF 1,4-EPIPEROXIDES

The Pd(PPh3)4 catalyzed reaction of 2,3-saturated and 2,3-unsaturated 1,4-epiperoxides proceeds by courses markedly different from those of the previously reported transition metal catalyses.The Pd(0)-promoted reaction of 2,3-saturated epiperoxides gives the corresponding 4-hydroxy ketones and 1,4-diols as the major products.From 2,3-dedihydroepiperoxides are formed the corresponding 4-hydroxy enones, syn-1,2;3,4-diepoxides, and 1,4-diols.The results are interpreted in terms of competing Pd(0)/Pd(II) exchange mechanisms.Exposure of prostaglandin (PG) H2 methyl esterto Pd(PPh3)4 produces a mixture of methyl esters of PGD2, PGE2, PGF2α, and (5Z,8E,10E,12S)-12-hydroxy-5,8,10-heptadecatrienoic acid.

PALLADIUM(O) CATALYZED REACTION OF 1,3-DIENE 1,4-EPIPEROXIDES

Reaction of 1,3-diene 1,4-epiperoxides with Pd(PPh3)4 catalyst forms the corresponding 4-hydroxy enones, syn diepoxides, and 1,4-diols as the major products.The results are interpreted as being due to competing Pd(O)/ Pd(II) and Pd(O)/ Pd(I) exchange mechanisms.