81238-83-7Relevant academic research and scientific papers
Synthesis and characterisation of severely hindered P-OR compounds
Williams, D. Bradley G.,Netshiozwi, Takelani E.
experimental part, p. 9973 - 9982 (2010/02/27)
P-Cl substrates were converted into their P-OR analogues from hindered alcohols using an amine base. Where the system was severely hindered, more forcing conditions were required that necessitated the presence of a metal alkoxide nucleophile before succes
ASYMMETRIC HYDROGENATION OF ENOL PHOSPHINATES CATALYZED BY A CHIRAL FERROCENYLPHOSPHINE- RHODIUM COMPLEX. ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE SECONDARY ALKYL ALCOHOLS
Hayashi, Tamio,Kanehira, Koichi,Kumada, Makoto
, p. 4417 - 4420 (2007/10/02)
Catalytic asymmetric synthesis of secondary alkyl alcohols (up to 78 percent ee) was accomplished by asymmetric hydrogenation of enol diphenylphosphinates, derived from prochiral ketones such as acetophenone, 3-methyl-2-butanone, and 2-octanone, in the presence of a cationic rhodium complex of (R)-1-ethanol (BPPFOH).
