81241-65-8

Usage

Appearance

Pale yellow liquid

Odor

Faint amine odor

Common uses

Surfactant, corrosion inhibitor, building block in the synthesis of pharmaceuticals and agrochemicals, production of personal care products, adhesives, and lubricants

Safety precautions

Can be harmful if ingested or inhaled, may cause skin and eye irritation upon contact

Upstream product

• 141-43-5 ethanolamine 
• 78-93-3 butanone 

Relevant academic research and scientific papers

High-Throughput Mass Spectrometry Screening Platform for Discovering New Chemical Reactions under Uncatalyzed, Solvent-Free Experimental Conditions

A gas-phase high-throughput reaction screening platform was developed for the first time to study chemical structures of closely related functional groups and for the discovery of novel organic reaction pathways. Experiments were performed using the contained atmospheric pressure chemical ionization (APCI) source that enabled nonthermal, nonequilibrium plasma chemistry to be monitored by mass spectrometry (MS) in real time. This contained-APCI MS platform allowed an array of reagents to be tested, resulting in the studies of multiple gas-phase reactions in parallel. By exposing headspace vapor of the selected reagents to corona discharge, solvent-free Borsche-Drecsel cyclization reaction, Katritzky chemistry, and Paal-Knorr pyrrole synthesis were examined in the gas phase, outside the high vacuum environment of the mass spectrometer. A new radical-mediated hydrazine coupling reaction was also discovered, which provided a selective pathway to synthesize secondary amines without using a catalyst. The mechanisms of these atmospheric pressure gas-phase reactions were explored through the direct capture of intermediates and via comparison with the corresponding bulk solution and droplet-phase reactions.

METHOD FOR PRODUCING 2-AMINOETHYLMETHACRYLATE HYDROCHLORIDE

Provided is a method for producing 2-aminoethyl methacrylate hydrochloride that, according to one embodiment, includes a step (A) for reacting a ketimine compound of 2-aminoethyl methacrylate with water and hydrogen chloride and obtaining a mixture containing 2-aminoethyl methacrylate hydrochloride, wherein in the step (A), the ratio of the total amount of hydrogen chloride to the total amount of ketimine compound of 2-aminoethyl methacrylate is 1.0-1.5 expressed in terms of equivalents, and the ratio of the total amount of water to the total amount of ketimine compound of 2-aminoethyl methacrylate is 1.0-2.0 expressed in terms of equivalents.

METHOD FOR PRODUCING KETIMINE COMPOUND OF 2-AMINO-ETHYL METHACRYLATE

PROBLEM TO BE SOLVED: To provide a method for producing a ketimine compound of 2-amino-ethyl methacrylate in high yield. SOLUTION: Provided is a method for producing a ketimine compound of 2-amino-ethyl methacrylate in which, in a step of reacting a ketimine compound of 2-amino-ethanol and methacrylic acid ester to produce a ketimine compound of 2-amino-ethyl (meth)acrylate represented by formula (3) or formula (4), the water concentration in the reaction raw material liquid is controlled to a predetermined value or less. (R1 and R2 represent a C1 to 12 alkyl group or the like.). (R3 represents a C3 to 10 divalent hydrocarbon group or the like). SELECTED DRAWING: None COPYRIGHT: (C)2017,JPOandINPIT