81262-74-0 Usage
Core structure
quinazoline core
Aromatic rings
one chlorophenyl group and one fluorophenyl group
Heterocyclic ring
piperazine ring
Functional groups
sulfanyl, oxo (carbonyl), and ethyl chain
Oxidation state
2-oxo-ethyl indicates a carbonyl group (C=O) connected to an ethyl group (CH3CH2)
Potential pharmaceutical applications
anticancer, antifungal, and antibacterial properties
Interaction with serotonin receptors
piperazine moiety suggests potential binding to serotonin receptors, which could be relevant for psychiatric or neurological drug targeting
Diverse biological activities
the presence of multiple functional groups and aromatic rings indicates a wide range of possible interactions with biological targets
Therapeutic potential
the combination of the quinazoline core and various functional groups suggests this compound may have multiple therapeutic applications
Check Digit Verification of cas no
The CAS Registry Mumber 81262-74-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,2,6 and 2 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 81262-74:
(7*8)+(6*1)+(5*2)+(4*6)+(3*2)+(2*7)+(1*4)=120
120 % 10 = 0
So 81262-74-0 is a valid CAS Registry Number.
InChI:InChI=1/C26H22ClFN4O2S/c27-18-8-10-20(11-9-18)30-12-14-31(15-13-30)24(33)17-35-26-29-23-7-2-1-6-22(23)25(34)32(26)21-5-3-4-19(28)16-21/h1-11,16H,12-15,17H2
81262-74-0Relevant articles and documents
Monoamine oxidase inhibitory and CNS activities of some quinazolinones
Lata,Satsangi,Srivastava,Kishor
, p. 24 - 27 (2007/10/02)
16 new compounds have been synthesised in the series of 3-aryl-2-(1'-aryl-piperazin-4'-yl-carboxamidomethyl)-mercapto-quinazolinones . The compounds showed interesting results in anticonvulsant, hypnotic and monoamine oxidase (MAO) inhibitory screenings a