812640-60-1Relevant academic research and scientific papers
Lewis acid-mediated selective chlorinations of silyl enolate
Zhang, Yanhua,Shibatomi, Kazutaka,Yamamoto, Hisashi
, p. 15038 - 15039 (2004)
A new method involving efficient, widely applicable, and highly selective α-chlorination of simple silyl enolate with Lewis acid and an α,α-dichloro-1,3-dicarbonyl controller unit was reported. Diastereoselectivity and enantioselectivity of the reaction were investigated. High reactivity and selectivity were achieved by using α,α-dichlorinated malonic ester. Copyright
