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(4-formyl-2,6-dimethoxyphenoxy)acetic acid is a chemical compound with the molecular formula C11H12O6, derived from acetic acid. It features a formyl group and two methoxy groups attached to a phenoxy ring, which contribute to its unique chemical properties and reactivity. (4-formyl-2,6-dimethoxyphenoxy)acetic acid is widely utilized in organic synthesis and pharmaceutical research, with its derivatives demonstrating potential as anti-inflammatory and antiproliferative agents. Furthermore, it has been investigated for its therapeutic potential in treating various diseases, such as cancer, inflammation, and cardiovascular disorders.

812642-73-2

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812642-73-2 Usage

Uses

Used in Pharmaceutical Research:
(4-formyl-2,6-dimethoxyphenoxy)acetic acid is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure and reactivity make it a valuable building block for developing new drugs with potential applications in treating a range of diseases.
Used in Organic Synthesis:
In the field of organic synthesis, (4-formyl-2,6-dimethoxyphenoxy)acetic acid serves as a versatile starting material for the creation of diverse chemical compounds. Its formyl and methoxy groups can be further modified or functionalized to produce a wide array of molecules with different properties and applications.
Used in Anti-inflammatory Applications:
(4-formyl-2,6-dimethoxyphenoxy)acetic acid and its derivatives have shown potential as anti-inflammatory agents. They may be used to develop new medications for the treatment of inflammation-related conditions, such as arthritis, asthma, and other autoimmune diseases.
Used in Anticancer Applications:
(4-formyl-2,6-dimethoxyphenoxy)acetic acid has been studied for its potential application in cancer treatment. Its derivatives have demonstrated antiproliferative properties, which could be harnessed to develop novel anticancer drugs that target cancer cell growth and proliferation.
Used in Cardiovascular Disorder Treatment:
(4-formyl-2,6-dimethoxyphenoxy)acetic acid has also been investigated for its potential in treating cardiovascular disorders. Its unique chemical structure may allow for the development of new therapeutic agents that can help manage or treat conditions such as hypertension, atherosclerosis, and heart failure.

Check Digit Verification of cas no

The CAS Registry Mumber 812642-73-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,1,2,6,4 and 2 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 812642-73:
(8*8)+(7*1)+(6*2)+(5*6)+(4*4)+(3*2)+(2*7)+(1*3)=152
152 % 10 = 2
So 812642-73-2 is a valid CAS Registry Number.

812642-73-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(4-formyl-2,6-dimethoxyphenoxy)acetic acid

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:812642-73-2 SDS

812642-73-2Downstream Products

812642-73-2Relevant academic research and scientific papers

Design, synthesis, and biological evaluation of thiazolidine-2,4-dione conjugates as PPAR-γ agonists

Nazreen, Syed,Alam, Mohammad Sarwar,Hamid, Hinna,Yar, Mohammad Shahar,Dhulap, Abhijeet,Alam, Perwez,Pasha, Mohammad Abdul Qadar,Bano, Sameena,Alam, Mohammad Mahboob,Haider, Saqlain,Kharbanda, Chetna,Ali, Yakub,Pillai, Kolakappi

, p. 421 - 432 (2015)

A library of synthesized conjugates of phenoxy acetic acid and thiazolidinedione 5a-m showed potent peroxisome proliferator activated receptor-γ (PPAR-γ) transactivation as well as significant blood glucose lowering effect comparable to the standard drugs pioglitazone and rosiglitazone. Most of the compounds showed higher docking scores than the standard drug rosiglitazone in the molecular docking study. Compounds 5l and 5m exhibited PPAR-γ transactivation of 54.21 and 55.41%, respectively, in comparison to the standard drugs pioglitazone and rosiglitazone, which showed 65.94 and 82.21% activation, respectively. Compounds 5l and 5m significantly lowered the blood glucose level of STZ-induced diabetic rats. Compounds 5l and 5m lowered the AST, ALT, and ALP levels more than the standard drug pioglitazone. PPAR-γ gene expression was significantly increased by compound 5m (2.00-fold) in comparison to the standard drugs pioglitazone (1.5-fold) and rosiglitazone (1.0-fold). Compounds 5l and 5m did not cause any damage to the liver and could be considered as promising candidates for the development of new antidiabetic agents.

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