812652-62-3

Upstream product

• 67-62-9 O-Methylhydroxylamin 
• 101096-90-6 2-hydroxy-3,3-diphenylpropanenitrile 
• 530-62-1 1,1'-carbonyldiimidazole 

Relevant academic research and scientific papers

Synthesis of novel 4-functionalised oxazolidin-2-ones

The synthesis of O-substituted and O-unsubstituted 3-hydroxy-4-thioxo- oxazolidin-2-ones, functionalised 4-imino-oxazolidine-2-ones and 4-phenoxy-imino-oxazolidin-2-one starting from O-substituted and O-unsubstituted 3-hydroxy-4-imino-oxazolidin-2-ones is described. A one-pot protocol for the preparation of 4-methoxyimino-, 4-aralkoxyimino- and 4-phenoxyimino-oxazolidin- 2-ones has been developed. Georg Thieme Verlag Stuttgart.

Efficient conversion of O-substituted 3-hydroxy-4-imino-oxazolidin-2-ones into O-substituted α-hydroxyamidoximes

(Chemical equation presented) An efficient and convenient two-step synthesis of O-substituted α-hydroxyamidoximes has been developed. The first step involves a high-yielding one-pot synthesis of the so far unknown O-substituted 3-hydroxy-4-imino-oxazolidin-2-ones by reacting cyanohydrins stepwise with 1,1′-carbonyldiimidazole and O-substituted hydroxylamines. The second step represents a novel, sodium methoxide-mediated conversion of O-substituted 3-hydroxy-4-imino-oxazolidin-2-ones into the corresponding O-substituted α-hydroxyamidoximes.