812652-68-9Relevant academic research and scientific papers
Efficient conversion of O-substituted 3-hydroxy-4-imino-oxazolidin-2-ones into O-substituted α-hydroxyamidoximes
Kurz, Thomas,Widyan, Khalid
, p. 4403 - 4405 (2007/10/03)
(Chemical equation presented) An efficient and convenient two-step synthesis of O-substituted α-hydroxyamidoximes has been developed. The first step involves a high-yielding one-pot synthesis of the so far unknown O-substituted 3-hydroxy-4-imino-oxazolidin-2-ones by reacting cyanohydrins stepwise with 1,1′-carbonyldiimidazole and O-substituted hydroxylamines. The second step represents a novel, sodium methoxide-mediated conversion of O-substituted 3-hydroxy-4-imino-oxazolidin-2-ones into the corresponding O-substituted α-hydroxyamidoximes.
