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Usage

Uses

Used in Chemical Synthesis:
3-(Nitromethyl)cyclopentanone is used as a synthetic intermediate for the preparation of various organic compounds. Its unique structure allows it to participate in a range of chemical reactions, making it a valuable component in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Laboratory Research:
3-(Nitromethyl)cyclopentanone is used as a research compound in academic and industrial laboratories. It serves as a model compound for studying the reactivity and properties of ketones and nitro groups, contributing to the advancement of organic chemistry and related fields.
Used in Material Safety:
3-(Nitromethyl)cyclopentanone is used as a reference material for the development and validation of Material Safety Data Sheets (MSDS). Its properties and potential hazards are documented to ensure that proper safety measures are in place for handling, storage, and disposal, thereby protecting the health and safety of individuals who work with 3-(nitromethyl)cyclopentanone.

Upstream product

• 930-30-3 cyclopent-2-enone 
• 75-52-5 nitromethane 
• 60410-16-4 (1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate 
• 3001-72-7 DBN 

Downstream Products

• 1260796-43-7 tert-butyl (3-hydroxycyclopentyl)methylcarbamate 
• 116649-87-7 3-(aminomethyl)cyclopentanol 
• 914930-87-3 N-{6,7-diethoxy-9-[3-(2-methyl-thiazol-4-yl)-phenylamino]-2,3-dihydro-1H-cyclopenta[b]quinolin-1-ylmethyl}-acetamide 
• 914930-89-5 N-{6,7-diethoxy-9-[3-(2-methyl-thiazol-4-yl)-phenylamino]-2,3-dihydro-1H-cyclopenta[b]quinolin-2-ylmethyl}-acetamide 
• 914931-04-7 (6,7-diethoxy-2-nitromethyl-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)[3-(2-methylthiazol-4-yl)phenyl]amine 
• 914931-03-6 (6,7-diethoxy-1-nitromethyl-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)[3-(2-methylthiazol-4-yl)phenyl]amine 

Relevant academic research and scientific papers

Unusual regioselectivity in Pd(0)-catalyzed coupling of allylic monoacetates and nitroalkanes: one-pot isomerization-alkylation

A hitherto unknown palladium-catalyzed reaction of nitroalkanes with hydroxy allylic acetates is reported. The reaction led to the formation of γ-nitrocarbonyl compounds instead of the usual unsaturated nitroalcohol expected upon displacement of the allylic acetate group.

Asymmetric conjugate addition of nitroalkanes to enones with a chiral α-aminophosphonate catalyst

Chiral diethyl (2R)-tetrahydropyrro-2-ylphosphonate is an effective catalyst for the Michael addition of nitroalkanes to α,β-unsaturated ketones. This study revealed that the hydrate salt of this α-aminophosphonate was found to be a better catalytic speci

Cycloalkyl-one-containing benzenesulphonamides

Cycloalkanol[1,2-b]indole-sulphonamides of the formula STR1 where appropriate in an isomeric form, and their salts are disclosed. These compounds are useful to inhibit platelet aggregation and to antagonize thromboxane A2.

CONJUGATE ADDITION OF ALIPHATIC NITRO COMPOUNDS TO 2-CYCLOPENTENONE

Conjugate addition of aliphatic nitro compounds to 2-cyclopentenone has been studied.The best results were obtained by the application of nitronate anions, prepared in situ with methanolic sodium methoxide solution.The adducts have been characterized by elemental analysis and spectroscopic data.