812684-99-4

Basic information

• Product Name: 2-(3-chloro-phenyl)-2-(4-methoxy-phenyl)-[1,3]dioxolane
• Synonyms: 2-(3-chloro-phenyl)-2-(4-methoxy-phenyl)-[1,3]dioxolane
• CAS NO: 812684-99-4
• Molecular Weight: 290.746
• Mol File: 812684-99-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(3-chloro-phenyl)-2-(4-methoxy-phenyl)-[1,3]dioxolane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-chloro-phenyl)-2-(4-methoxy-phenyl)-[1,3]dioxolane(812684-99-4)
• EPA Substance Registry System: 2-(3-chloro-phenyl)-2-(4-methoxy-phenyl)-[1,3]dioxolane(812684-99-4)

Safety Data

• Hazardous Substances Data: 812684-99-4(Hazardous Substances Data)

Upstream product

• 13389-51-0 (3-chlorophenyl)(4-methoxyphenyl)methanone 
• 107-21-1 ethylene glycol 

Relevant articles and documents

Lithiation of 2-aryl-2-(chloroaryl)-1,3-dioxolanes and its application in the synthesis of new ortho-functionalized benzophenone derivatives

2-Aryl-2-(chloroaryl)-1,3-dioxolanes 4 were lithiated ortho to the ketal group of the chloroaryl ring by treatment with butyllithium in THF between -78 and 0°C. The site selectivity of some of the deprotonation reactions was rationalized by the long-range effect of the 4-chloro substituent. The lithio species thus generated were treated with various electrophiles to give ortho-functionalized benzophenone derivatives. Intramolecular competition between the aryl rings was observed in the lithiation of 2-(4-chlorophenyl)-2- (4-fluorophenyl)-1,3-dioxolane (4s). Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.