812699-84-6

Basic information

• Product Name: N-[4-methyl-3-(4-pyrazin-2-yl-pyrimidin-2-ylamino)-phenyl]-3-(2,2,2-trifluoroethoxy)benzamide
• Synonyms: N-[4-methyl-3-(4-pyrazin-2-yl-pyrimidin-2-ylamino)-phenyl]-3-(2,2,2-trifluoroethoxy)benzamide
• CAS NO: 812699-84-6
• Molecular Weight: 480.449
• Mol File: 812699-84-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-[4-methyl-3-(4-pyrazin-2-yl-pyrimidin-2-ylamino)-phenyl]-3-(2,2,2-trifluoroethoxy)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[4-methyl-3-(4-pyrazin-2-yl-pyrimidin-2-ylamino)-phenyl]-3-(2,2,2-trifluoroethoxy)benzamide(812699-84-6)
• EPA Substance Registry System: N-[4-methyl-3-(4-pyrazin-2-yl-pyrimidin-2-ylamino)-phenyl]-3-(2,2,2-trifluoroethoxy)benzamide(812699-84-6)

Safety Data

• Hazardous Substances Data: 812699-84-6(Hazardous Substances Data)

Upstream product

• 641615-38-5 4-methyl-N*3*-(4-pyrazin-2-yl-pyrimidin-2-yl)-benzene-1,3-diamine 
• 35480-48-9 3-(2,2,2-trifluoroethoxy)benzoic acid 

Relevant articles and documents

2-AMINOPYRIMIDINE DERIVATIVES AS RAF KINASE INHIBITORS

This application discloses compounds that inhibit Raf kinase having the formula (I), wherein R1 is a phenyl radical or a heteroaryl radical; and R2 is a phenyl radical; or an N-oxide or a pharmaceutically acceptable salt thereof. The compounds are useful for the treatment of proliferative diseases, such as cancer.