81281-58-5 Usage
General Description
7-Aminotheophylline is a derivative of theophylline, a xanthine compound that is structurally similar to caffeine. It exerts its effects by acting as a phosphodiesterase inhibitor, which leads to increased levels of cAMP and subsequent relaxation of bronchial smooth muscles. It is commonly used as a bronchodilator to relieve symptoms of asthma and chronic obstructive pulmonary disease (COPD). Additionally, 7-Aminotheophylline also has diuretic and cardiac stimulant effects, making it useful in the treatment of heart failure and edema. It is important to note that 7-Aminotheophylline should be used cautiously, as it has a narrow therapeutic window and can cause adverse effects such as nausea, vomiting, and palpitations when taken in excessive amounts.
Check Digit Verification of cas no
The CAS Registry Mumber 81281-58-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,2,8 and 1 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 81281-58:
(7*8)+(6*1)+(5*2)+(4*8)+(3*1)+(2*5)+(1*8)=125
125 % 10 = 5
So 81281-58-5 is a valid CAS Registry Number.
InChI:InChI=1/C7H9N5O2/c1-10-5-4(12(8)3-9-5)6(13)11(2)7(10)14/h3H,8H2,1-2H3
81281-58-5Relevant articles and documents
PURINES, PYRIMIDINES, AND CONDENSED SYSTEMS BASED ON THEM. V. N-AMINOGROUP AS A PROTECTING FUNCTION IN PRODUCTION OF UNSYMMETRICAL 1,3-DIALKYLXANTHINES FROM 3-METHYLXANTHINE
Kuz'menko, V. V.,Gulevskaya, A. V.,Pozharskii, A. F.
, p. 1373 - 1377 (2007/10/02)
3-Methyl-7-aminoxanthine (yield 67percent) and 3-methyl-1,7-diaminoxanthine (7percent) were obtained by the amination of 3-methylxanthine by hydroxylamino-O-sulfonic acid in an alkaline medium.Alkylation of the 3-methyl-7-aminoxanthine potassium salt followed by removal of the N-amino group with nitrous acid led to the formation of 1-R-3-methylxanthines (R = C2H5, C6H5CH2, CH2CN, CH2CO2CH3) with good yields.
O-Diphenylphosphinylhydroxylamin (DPH), ein elektrophiles N-Aminierungsmittel
Kloetzer, Wilhelm,Baldinger, Helga,Karpitschka, Eva Maria,Knoflach, Johann
, p. 592 - 595 (2007/10/02)
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