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• 31236-71-2 lysichitalexin 
• 90-02-8 salicylaldehyde 
• 3179-10-0 1-methoxy-4-(2-nitro-vinyl)-benzene 

Relevant academic research and scientific papers

Syntheses of 2-Benzylbenzofuran Derivatives and 2-Aryl-nitrochroman Derivatives from Nitroalkene Precursors

Simple and straightforward methods for the synthesis of 2-benzylbenzofuran, 3-substituted 2-benzylbenzofuran, and 2-aryl-nitrochroman derivatives are described. Benzofurans were generated from nitroalkenes by reduction with NaBH4 followed by a Nef reaction and acid-mediated cyclization, whereas 3-substituted 2-benzylbenzofurans were prepared from nitroalkenes by reactions with Grignard reagents followed by a Nef reaction and an acid-mediated cyclization in a one-pot process. The synthesis of chromans involved a Knoevenagel condensation and the 1,4-diazabicyclo[2.2.2]octane (DABCO) assisted cyclization of β-(2-hydroxyphenyl)-nitroethanes and benzaldehydes, also in a one-pot process. Simple and convenient methods for the synthesis of 2-benzylbenzofuran, 3-substituted 2-benzylbenzofuran, and 2-aryl-nitrochroman derivatives are described.

Sodium Borohydride Reduction of 3-Nitro-2-substituted-phenyl-2H-benzopyrans

Reaction of 3-nitro-2-substituted-phenyl-2H-benzopyrans (1-8) with NaBH4 at 5-10 deg C followed by reduction of the nitro group with hydrazine hydrate in the presence of Raney-nickel furnishes 3-amino-2-substituted-phenyl-3,4-dihydro-2H-benzopyrans