81306-29-8Relevant academic research and scientific papers
A Regioselective Annulation of Butenolides. The Total Synthesis of (+/-) Confertifolin
Jansen, Ben J. M.,Bouwman, Catharina T.,Groot, Aede de
, p. 2977 - 2980 (2007/10/02)
γ-(Phenylsulfinyl)-α,β-unsaturated aldehydes 2, prepared from α-(n-butylthio)methylene ketones 1 via addition of lithium followed by hydrolysis and oxidation, are converted into butenolides 4 or 5 depending upon the reaction conditions.
Synthesis of the Drimane-related Sesquiterpenes Euryfuran, Confertifolin, and Valdiviolide
Ley, Steven V.,Mahon, Michael
, p. 1379 - 1381 (2007/10/02)
trans-3,4,4a,5,6,7,8,8a-Octahydro-5,5,8a-trimethylnaphthalene-1-(2H)-one (1) was converted into the drimane sesquiterpene euryfuran (5) in 59percent yield.Euryfuran was then used as a starting material for the synthesis two other drimane natural products, confertifolin and valdiviolide.The preparation of valdiviolide constitutes the first total synthesis of this molecule.
