81319-59-7

Basic information

• Product Name: 7-Methyladenosine Perchlorate Salt
• Synonyms: 7-Methyladenosine Perchlorate Salt;ZYUYMHDZDDBZKY-UHFFFAOYSA-O
• CAS NO: 81319-59-7
• Molecular Formula: C11H16ClN5O8
• Molecular Weight: 381.72644
• Product Categories: Miscellaneous Reagents, Nucleotides, Bases & Related Reagentsm
• Mol File: 81319-59-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: DMSO (Slightly), Methanol (Very Slightly, Sonicated), Water (Very Slightly)
• Stability: Hygroscopic
• CAS DataBase Reference: 7-Methyladenosine Perchlorate Salt(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Methyladenosine Perchlorate Salt(81319-59-7)
• EPA Substance Registry System: 7-Methyladenosine Perchlorate Salt(81319-59-7)

Safety Data

• Hazardous Substances Data: 81319-59-7(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 81319-59-7 differently. You can refer to the following data:
1. As perchlorate salt derivative of Adenosine (A280400), nucleotide, 7-Methyladenosine Perchlorate Salt is also used in the synthesis of 2’-deoxy-7-methyladenosine.
2. Perchlorate salt derivative of Adenosine (A280400), nucleotide. It is also used in the synthesis of 2’-deoxy-7-methyladenosine.

Upstream product

• 19399-25-8 N⁶-methoxyadenosine 

Relevant articles and documents

SYNTHESIS AND GLYCOSIDIC BOND CLEAVAGE OF 7-METHYL- AND 7-ETHYL-ADENOSINES: AN ALTERNATIVE SYNTHESIS OF 7-ALKYLADENINES

7-Methyladenosine perchlorate (VIIa: X = ClO4) was prepared in pure and crystalline form from N6-methoxyadenosine (I) by methylation with MeI at the 7-position followed by catalytic hydrogenolysis of the N6-methoxy group. 7-Ethyladenosine perchlorate (VIIb: X = ClO4) was also synthesized from N6-benzyloxyadenosine (II) in an analogous manner.On treatment with H2O at 98-100 deg C for 40 min, VIIa (X = ClO4) and VIIb (X = ClO4) produced 7-methyladenine (VIIIa) and 7-ethyladenine (VIIIb) in 84percent and 55percent yields.In 0.1 N aqueous HCl at 25 deg C, VIIa (X = ClO4) and VIIb (X = ClO4) were hydrolyzed in similar manners at rates of 2.22E-3 min-1 and 1.69E-3 min-1, respectively.Comparison of these rate conctants with those of other three N-methyladenosine isomers X, XI, and XII has revealed that the relative ease of the hydrolysis of the glycosidic bond is in the order of 3- (XI) > 7- (VIIa) >> N6- (X) >/= 1-methyladenosine (XII).