81319-59-7 Usage
Uses
Used in Pharmaceutical Industry:
7-Methyladenosine Perchlorate Salt is used as an intermediate in the synthesis of 2'-deoxy-7-methyladenosine, a modified nucleoside with potential therapeutic applications. 7-Methyladenosine Perchlorate Salt can be further utilized in the development of novel drugs targeting various diseases, including cancer and viral infections.
Used in Chemical Synthesis:
As a perchlorate salt derivative of Adenosine, 7-Methyladenosine Perchlorate Salt serves as a valuable building block in the synthesis of other nucleotide analogs and modified nucleic acids. These modified molecules can be employed in research and development for understanding the structure-function relationships in nucleic acids and their interactions with proteins and other biomolecules.
Check Digit Verification of cas no
The CAS Registry Mumber 81319-59-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,3,1 and 9 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 81319-59:
(7*8)+(6*1)+(5*3)+(4*1)+(3*9)+(2*5)+(1*9)=127
127 % 10 = 7
So 81319-59-7 is a valid CAS Registry Number.
81319-59-7Relevant academic research and scientific papers
SYNTHESIS AND GLYCOSIDIC BOND CLEAVAGE OF 7-METHYL- AND 7-ETHYL-ADENOSINES: AN ALTERNATIVE SYNTHESIS OF 7-ALKYLADENINES
Fujii, Tozo,Saito, Tohru
, p. 117 - 123 (2007/10/02)
7-Methyladenosine perchlorate (VIIa: X = ClO4) was prepared in pure and crystalline form from N6-methoxyadenosine (I) by methylation with MeI at the 7-position followed by catalytic hydrogenolysis of the N6-methoxy group. 7-Ethyladenosine perchlorate (VIIb: X = ClO4) was also synthesized from N6-benzyloxyadenosine (II) in an analogous manner.On treatment with H2O at 98-100 deg C for 40 min, VIIa (X = ClO4) and VIIb (X = ClO4) produced 7-methyladenine (VIIIa) and 7-ethyladenine (VIIIb) in 84percent and 55percent yields.In 0.1 N aqueous HCl at 25 deg C, VIIa (X = ClO4) and VIIb (X = ClO4) were hydrolyzed in similar manners at rates of 2.22E-3 min-1 and 1.69E-3 min-1, respectively.Comparison of these rate conctants with those of other three N-methyladenosine isomers X, XI, and XII has revealed that the relative ease of the hydrolysis of the glycosidic bond is in the order of 3- (XI) > 7- (VIIa) >> N6- (X) >/= 1-methyladenosine (XII).
