813414-99-2Relevant academic research and scientific papers
Alkynyl halides in ruthenium(II)-catalyzed [2+2] cycloadditions of bicyclic alkenes
Allen, Anna,Villeneuve, Karine,Cockburn, Neil,Fatila, Elisabeth,Riddell, Nicole,Tam, William
experimental part, p. 4178 - 4192 (2009/05/27)
Ru-catalyzed [2+2] cycloadditions between bicyclic alkenes and alkynyl halides were found to occur in moderate to good yields. The presence of the halide moiety greatly enhances the reactivity of the alkyne component in the cycloaddition and can be transformed into a variety of products that are difficult or impossible to obtain by direct cycloaddition. Wiley-VCH Verlag GmbH & Co. KGaA, 2008.
Ruthenium-catalyzed [2+2] cycloadditions of alkynyl sulfides and alkynyl sulfones
Riddell, Nicole,Tam, William
, p. 1934 - 1937 (2007/10/03)
Ruthenium-catalyzed [2+2] cycloadditions of bicyclic alkenes with alkynyl sulfides and alkynyl sulfones were investigated. The sulfide and sulfone moieties were found to be compatible with the Ru-catalyzed cycloadditions, giving the corresponding cyclobut
Study on the reactivity of the alkyne component in ruthenium-catalyzed [2 + 2] cycloadditions between an alkene and an alkyne
Jordan, Robert W.,Villeneuve, Karine,Tam, William
, p. 5830 - 5833 (2007/10/03)
The ruthenium-catalyzed [2 + 2] cycloadditions of norbornadiene with a variety of alkynes have been investigated. Electronic effect of the alkyne component has shown to play an important role on the rate of the cycloaddition, and the reactivity of the alkyne component increases dramatically as the alkyne becomes more electron deficient. Increase in the steric bulk of the alkyne component decreases the reactivity of the alkyne component. It was also found that chelation effect of propargylic alcohols greatly enhanced the reactivity of the alkyne component in the ruthenium-catalyzed [2 + 2] cycloadditions.
Ruthenium-catalyzed [2 + 2] cycloadditions between bicyclic alkenes and alkynyl halides
Villeneuve, Karine,Riddell, Nicole,Jordan, Robert W.,Tsui, Gavin C.,Tam, William
, p. 4543 - 4546 (2007/10/03)
(Chemical equation presented) Ru-catalyzed [2 + 2] cycloadditions between norbornadiene and alkynyl halides were found to occur in moderate to good yields (32-89%). The presence of the halide moiety greatly enhances the reactivity of the alkyne component in the cycloaddition and can be transformed into a variety of products that are difficult or impossible to obtain via direct cycloaddition.
