813445-94-2Relevant academic research and scientific papers
Synthesis of N-substituted-2-aminobenzothiazoles using nano copper oxide as a recyclable catalyst under ligand-free conditions, in reusable PEG-400 medium
Gaddam, Satish,Kasireddy, Harshavardhan Reddy,Konkala, Karnakar,Katla, Ramesh,Durga, Nageswar Yadavalli Venkata
, p. 732 - 736 (2014/06/09)
A simple and practical method for the synthesis of N-substituted-2- aminobenzothiazoles via a cross-coupling reaction of 2-iodo anilines with isothiocyanates is envisaged using nano copper oxide as a recyclable catalyst and Cs2CO3 as a base in PEG-400, as a bio-degradable, reusable, inexpensive and non-toxic reaction medium, under ligand-free conditions. The present tandem process underlines environmental acceptability to access a wide range of N-substituted-2-aminobenzothiazoles in good to excellent yields.
