81363-78-2

Basic information

• Product Name: alpha-monofluoromethyltyrosine methyl ester
• Synonyms: alpha-monofluoromethyltyrosine methyl ester
• CAS NO: 81363-78-2
• Molecular Formula: C₁₁H₁₄FNO₃
• Molecular Weight: 0
• Mol File: 81363-78-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 371.6°C at 760 mmHg
• Flash Point: 178.6°C
• Appearance: /
• Density: 1.242g/cm³
• Vapor Pressure: 4.76E-06mmHg at 25°C
• Refractive Index: 1.536
• CAS DataBase Reference: alpha-monofluoromethyltyrosine methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: alpha-monofluoromethyltyrosine methyl ester(81363-78-2)
• EPA Substance Registry System: alpha-monofluoromethyltyrosine methyl ester(81363-78-2)

Safety Data

• Hazardous Substances Data: 81363-78-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H14FNO3/c1-16-10(15)11(13,7-12)6-8-2-4-9(14)5-3-8/h2-5,14H,6-7,13H2,1H3/t11-/m1/s1

Upstream product

• 73804-76-9 α-fluoromethyl-p-tyrosine 
• 3417-91-2 tyrosine methyl ester hydrochloride 
• 69955-04-0 2-benzylideneamino-3-(4-hydroxyphenyl)-propionic acid methyl ester 
• 153711-34-3 methyl-α-fluoromethyl-N-benzylidene-p-tyrosinate 

Downstream Products

• 73804-76-9 α-fluoromethyl-p-tyrosine 

Relevant articles and documents

Direct synthesis of 3-fluoro-α-fluoromethyl-p-tyrosine

3-Fluoro-α-fluoromethyl-p-tyrosine was synthesized directly by the reaction of acetyl hypofluorite with α-fluoromethyl-p-tyrosine. α-Fluoromethyl-p-tyrosine was prepared by a four-step reaction while acetyl hypofluorite was prepared from elemental fluorin

Method of depleting endogenous monoamines

2-Amino-2-fluoromethyl-3-(substituted)phenyl propionic acids and derivatives thereof are coadministered with dopamine for the treatment of schizophrenia, mania, tardive dyskinesia, anxiety, or depression.