81371-01-9

Basic information

• Product Name: (-)-(2R,5R)-trans-2,5-bis(tosylmethyl)tetrahydrofuran
• CAS NO: 81371-01-9
• Molecular Weight: 440.538
• Mol File: 81371-01-9.mol

Chemical Properties

• CAS DataBase Reference: (-)-(2R,5R)-trans-2,5-bis(tosylmethyl)tetrahydrofuran(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-(2R,5R)-trans-2,5-bis(tosylmethyl)tetrahydrofuran(81371-01-9)
• EPA Substance Registry System: (-)-(2R,5R)-trans-2,5-bis(tosylmethyl)tetrahydrofuran(81371-01-9)

Safety Data

• Hazardous Substances Data: 81371-01-9(Hazardous Substances Data)

Upstream product

• 81370-98-1 (+)-(2R,5R)-trans-2,5-bis(methoxycarbonyl)tetrahydrofuran 
• 81370-94-7 (+)-trans-tetrahydrofuran-2,5-dicarboxylic acid 
• 81370-89-0 (-)-(2R,5R)-trans-2,5-bis(hydroxymethyl)tetrahydrofuran 
• 98-59-9 p-toluenesulfonyl chloride 

Relevant articles and documents

Synthesis of Stereoisomeric Crown Ethers Composed of cis- and trans-2,5-Bis(hydroxymethyl)tetrahydrofuran Units and Their Selective Transport of Alkali Metal Cations through Liquid Membranes

Optical resolution of trans-tetrahydrofuran-2,5-dicarboxylic acid (13) was carried out via the (+)-2-(1-aminoethyl)naphthalene salt, and conversion of the (+) enantiomer 13 into (+)-2,5-dimethyltetrahydrofuran (17) of known configuration established its 2R,5R configuration.Condensation of (+)- and (-)-trans-ditosylates 15 and cis-ditosylate 20 with pyrocatechol afforded (-)-D2-trans,trans-8, (-)-C1-cis,trans-9, meso-C2h-trans,trans-10, and a mixture of meso-C2h-11 and meso-C2v-cis,cis crown ethers 12.Their selective transport of alkali metal cations is reported.