81376-56-9Relevant academic research and scientific papers
Chan-Lam cross-coupling reaction based on the Cu2S/TMEDA system
Janíková, Kate?ina,Jedinák, Luká?,Volná, Tereza,Canka?, Petr
, p. 606 - 617 (2018/01/01)
A catalyst based on the readily available Cu2S/TMEDA system using a stable copper(I) source was developed for the Chan-Lam cross-coupling reaction. The capability of the catalyst was demonstrated with 1H-benzo[d]imidazol-2(3H)-one, 1H-benzo[d]imidazole, and 1H-imidazole together with electron-deficient, electron-rich, and sterically demanding boronic acids at room temperature in the presence of atmospheric oxygen to give the cross-coupling products in moderate to excellent yields. In addition, the coupling reaction of 1H-benzo[d]imidazole with several pinacol or neopentylglycol boronates indicated further potential of the catalyst. The reaction conditions tolerate the hydroxyl and bromo functional groups. The catalytic system also enables to synthesize the mono-N-substituted anilines from primary aliphatic amines. However, the two model compounds for the secondary and aromatic amines, piperidine and aniline, do not react. Two sterically demanding products with the restricted C–N bond rotation, synthesized by the N-arylation of 1H-benzo[d]imidazol-2(3H)-one with o-tolylboronic acid, enabled to confirm the atropisomers prepared by the Chan-Lam cross-coupling reaction. Furthermore, an example of one-pot Chan-Lam and Suzuki-Miyaura reaction has been reported.
Bay functionalized perylenediimide as a deaggregation based intracellular fluorescent probe for perchlorate
Singh, Prabhpreet,Mittal, Lalit Singh,Vanita, Vanita,Kumar, Rahul,Bhargava, Gaurav,Walia, Amandeep,Kumar, Subodh
supporting information, p. 13994 - 13997 (2015/11/17)
The aggregates of perylenediimide based chemosensor (PDI 1) undergo de-aggregation induced fluorescence quenching selectively with ClO4-ions both in the solution and in the solid phase and can detect ClO4-ions in drinking water and fireworks. PDI 1 is permeable to C6 glioma cells, and ClO4-can be detected using confocal microscopy.
