81387-53-3

Basic information

• Product Name: DL-PHENYLALANINE-15N
• Synonyms: DL-PHENYLALANINE-15N;DL-Phenylalanine-15N,99 atom % 15N;DL-PHENYLALANINE-15N, 98 ATOM % 15N
• CAS NO: 81387-53-3
• Molecular Formula: C9H11NO2
• Molecular Weight: 166.2
• Product Categories: Alphabetical Listings;P;Stable Isotopes
• Mol File: 81387-53-3.mol
• Article Data: 5

Chemical Properties

• Melting Point: 266-267 °C (dec.)(lit.)
• Appearance: /
• Density: 1.201g/cm³
• Refractive Index: 1.576
• CAS DataBase Reference: DL-PHENYLALANINE-15N(CAS DataBase Reference)
• NIST Chemistry Reference: DL-PHENYLALANINE-15N(81387-53-3)
• EPA Substance Registry System: DL-PHENYLALANINE-15N(81387-53-3)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 81387-53-3(Hazardous Substances Data)

Usage

General Description

DL-PHENYLALANINE-15N is a stable isotope-labeled form of the essential amino acid phenylalanine. It is commonly used in stable isotope labeling studies to trace the metabolic fate of phenylalanine in biological systems. DL-PHENYLALANINE-15N is labeled with the stable isotope nitrogen-15, which allows for accurate quantification and tracing of phenylalanine in metabolic pathways and protein synthesis processes. DL-PHENYLALANINE-15N is an important tool in biochemical and medical research to study the metabolism and functions of phenylalanine in various biological processes.

InChI:InChI=1/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/i10+1

Upstream product

• 114-76-1 sodium phenylphyruvate 

Downstream Products

• 127413-52-9 (S)-3-benzamido-3-phenylpropanoic acid 

Relevant articles and documents

AROMATIC AMINO ACID LABELED WITH STABLE ISOTOPE, METHOD FOR INCORPORATING THE SAME INTO TARGET PROTEIN AND METHOD FOR ANALYZING PROTEIN STRUCTURE USING NMR

The present invention herein provides, for instance, a stable isotope-labeled phenylalanine wherein a carbon atom of the phenyl group linked to an amino acid residue is 13C, 2 to 4 carbon atoms of the remaining 5, carbon atoms constituting the

STABLE ISOTOPE-LABELED AMINO ACID, METHOD OF INTEGRATING THE SAME INTO TARGET PROTEIN, METHOD OF NMR STRUCTURAL ANALYSIS OF PROTEIN AND PROCESS FOR PRODUCING SITE-SELECTIVE STABLE ISOTOPE-LABELED FUMARIC ACID AND TARTARIC ACID

The present invention provides a stable isotope-labeled amino acid which is at least one of amino acids constituting a protein and which has at least one of the following labeling patterns:(a) hydrogen atoms except at least one hydrogen atom in one or more methylene groups are deuterated,(b) hydrogen atoms in one of prochiral gem-methyl groups are completely deuterated,(c) hydrogen atoms in prochiral methyl groups are partially deuterated, and(d) all hydrogen atoms except one of them in methyl group are deuterated and hydrogen atoms in the aromatic ring are partially deuterated. With the stable isotope-labeled amino acid, the deuteration of protein can be attained without damaging the NMR sensitivity of remaining hydrogen nucleus and, in addition, the rapid, accurate analysis of NMR spectrum of a high-molecular protein which is beyond the limitation in the prior art and the determination of the stereo-structure can be performed at the same time.

Chemo-Enzymatic Syntheses of Isotopically Labelled L-Amino Acids

L-Alanine labelled with carbon-13 and nitrogen-15 has been prepared in good yield and high optical purity from achiral precursors using alanine dehydrogenase.This versatile approach may be simply adapted for the preparation of a range of isotopically labe