81411-64-5 Usage
General Description
1H-Pyrazolo[3,4-b]pyrazin-3-amine is a chemical compound with the molecular formula C6H6N6. It is a heterocyclic organic compound that consists of a pyrazinone ring fused with a pyrazole ring. 1H-Pyrazolo[3,4-b]pyrazin-3-amine is a potent inhibitor of the enzyme c-Jun N-terminal kinase (JNK), which plays a role in cell proliferation, apoptosis, and differentiation. 1H-Pyrazolo[3,4-b]pyrazin-3-amine has been studied for its potential therapeutic applications in cancer treatment, as blocking the JNK enzyme can inhibit the growth and survival of cancer cells. It is also being researched for its potential in neurodegenerative diseases and inflammatory conditions. Due to its pharmacological properties, this compound is of interest to researchers in medicinal chemistry and drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 81411-64-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,4,1 and 1 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 81411-64:
(7*8)+(6*1)+(5*4)+(4*1)+(3*1)+(2*6)+(1*4)=105
105 % 10 = 5
So 81411-64-5 is a valid CAS Registry Number.
InChI:InChI=1/C5H5N5/c6-4-3-5(10-9-4)8-2-1-7-3/h1-2H,(H3,6,8,9,10)
81411-64-5Relevant articles and documents
PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA
-
Page/Page column 67; 68, (2017/09/02)
Provided herein is a compound of formula (I), optionally in the form of a pharmaceutically acceptable salt, solvate, polymorph, prodrug, codrug, cocrystal, tautomer, racemate, enantiomer,or diastereomer or mixture thereof, which is useful in treating, ameliorating or preventing influenza.
NEW SYNTHETIC APPROACH FOR PYRAZOLOPYRAZINES AND ISOXAZOLOPYRAZINES
Kocevar, Marjan,Tisler, Miha,Stanovnik, Branko
, p. 339 - 342 (2007/10/02)
A new synthetic approach has been developed for the synthesis of pyrazolepyrazines (7) and isoxazolopyrazines (22) from the corresponding substituted pyrazines.
