81411-79-2Relevant academic research and scientific papers
A high-yielding method for the preparation of isoxazolopyridin-3-amine derivatives
Yu, Wensheng,Bulger, Paul G.,Maloney, Kevin M.
, p. 4941 - 4946 (2016/10/12)
A highly efficient and green method has been developed for the rapid preparation of highly functionalized isoxazolopyridin-3-amine derivatives in excellent yields. This process has a broad substrate scope, is operationally simple, and generally requires no chromatographic purification. In addition, the process is scalable and significantly greener than current alternatives with a PMI of 18 and water as the reaction solvent.
NEW SYNTHETIC APPROACH FOR PYRAZOLOPYRAZINES AND ISOXAZOLOPYRAZINES
Kocevar, Marjan,Tisler, Miha,Stanovnik, Branko
, p. 339 - 342 (2007/10/02)
A new synthetic approach has been developed for the synthesis of pyrazolepyrazines (7) and isoxazolopyrazines (22) from the corresponding substituted pyrazines.
Neighbouring Group Participation in Formation of Condensed Azines. Formation of Pyrazolo(3,4-b)pyrazines, Isoxazolo(4,5-b)pyrazines and Isothiazolo(5,4-b)pyridine (Heterocycles, CCX)
Kocevar, Marjan,Vercek, Bojan,Stanovnik, Branko,Tisler, Miha
, p. 731 - 744 (2007/10/02)
Pyrazine- and pyridinecarboxamidoximes with an amino, potentially tautomeric hydroxy or mercapto group in ortho position could be transformed in the appropriate condensed azines.In this manner, representatives of pyrazolo(3,4-b)pyrazine, isoxazolo(4,5-b)pyrazine and isothiazolo(5,4-b)pyridine ring system were synthesized and some transformations investigated. - Keywords: Cyclization with N-N, N-O or N-S bond formation; Heterocyclic compounds
