81411-79-2

Basic information

• Product Name: 3-AMINOISOXAZOLO[4,5-B]PYRAZINE
• Synonyms: 3-AMINOISOXAZOLO[4,5-B]PYRAZINE;[1,2]oxazolo[4,5-b]pyrazin-3-aMine;isoxazolo[4,5-b]pyrazin-3-amine
• CAS NO: 81411-79-2
• Molecular Formula: C5H4N4O
• Molecular Weight: 136.11
• Mol File: 81411-79-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 349.961°C at 760 mmHg
• Flash Point: 165.451°C
• Appearance: /
• Density: 1.542g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.721
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 3-AMINOISOXAZOLO[4,5-B]PYRAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINOISOXAZOLO[4,5-B]PYRAZINE(81411-79-2)
• EPA Substance Registry System: 3-AMINOISOXAZOLO[4,5-B]PYRAZINE(81411-79-2)

Safety Data

• Hazardous Substances Data: 81411-79-2(Hazardous Substances Data)

Usage

General Description

3-AminoIsoxazolo[4,5-b]Pyrazine is a chemical compound whose functional groups include pyrazines and isoxazoles. Pyrazines are aromatic compounds that contribute significantly to flavors and aromas, particularly those found in foods such as chocolate, coffee, and various types of fruits. Isoxazoles, on the other hand, are organic compounds and heterocycles which have a variety of biological activities and could have potential in therapeutic applications. More specific details about 3-AminoIsoxazolo[4,5-b]Pyrazine, such as its physical and chemical properties or potential uses and applications, are not widely reported in the literature.

InChI:InChI=1/C5H4N4O/c6-4-3-5(10-9-4)8-2-1-7-3/h1-2H,(H2,6,9)

Upstream product

• 55557-52-3 2-chloro-3-cyanopyrazine 
• 81411-73-6 2-oxo-1,2-dihydropyrazine-3-carboxamide O-acetyloxime 
• 81411-72-5 2-oxo-1,2-dihydropyrazine-3-carboxamide oxime 
• 81411-74-7 3-(N,N-dimethylaminomethyleneamino)-isoxazolo<4,5-b>pyrazine 

Downstream Products

• 81411-78-1 3-cyano-2(1H)-pyrazinone 
• 83410-12-2 3-(1,2,4-oxadiazolyl-3)-2(1H)-pyrazinone 

Relevant articles and documents

A high-yielding method for the preparation of isoxazolopyridin-3-amine derivatives

A highly efficient and green method has been developed for the rapid preparation of highly functionalized isoxazolopyridin-3-amine derivatives in excellent yields. This process has a broad substrate scope, is operationally simple, and generally requires no chromatographic purification. In addition, the process is scalable and significantly greener than current alternatives with a PMI of 18 and water as the reaction solvent.

Neighbouring Group Participation in Formation of Condensed Azines. Formation of Pyrazolo(3,4-b)pyrazines, Isoxazolo(4,5-b)pyrazines and Isothiazolo(5,4-b)pyridine (Heterocycles, CCX)

Pyrazine- and pyridinecarboxamidoximes with an amino, potentially tautomeric hydroxy or mercapto group in ortho position could be transformed in the appropriate condensed azines.In this manner, representatives of pyrazolo(3,4-b)pyrazine, isoxazolo(4,5-b)pyrazine and isothiazolo(5,4-b)pyridine ring system were synthesized and some transformations investigated. - Keywords: Cyclization with N-N, N-O or N-S bond formation; Heterocyclic compounds