81429-06-3Relevant academic research and scientific papers
Synthesis, Pharmacological Effects, and Conformation of 4,4-Disubstituted 1,4-Dihydropyridines
Goldmann, Siegfried,Born, Liborius,Kazda, Stanislav,Pittel, Bernd,Schramm, Matthias
, p. 1413 - 1418 (2007/10/02)
4,4-Disubstituted 1,4-dihydropyridines are synthesized by intramolecular addition of sulfinyl carbanions to pyridines.These disubstituted derivatives show a loss of Ca antagonistic potency of up to three powers of 10 both in vitro on aortic rings and in v
