81436-87-5

Upstream product

• 1079-66-9 chloro-diphenylphosphine 
• 140-28-3 N,N'-Dibenzylethylenediamine 

Downstream Products

• 229184-82-1 Ni(CO)2((C₆H₅)2PN(CH₂C₆H₅)CH₂CH₂N(CH₂C₆H₅)P(C₆H₅)2) 
• 229184-83-2 PdCl₂((C₆H₅)2PN(CH₂C₆H₅)CH₂CH₂N(CH₂C₆H₅)P(C₆H₅)2) 
• 229184-81-0 (C₅H₅)RuCl((C₆H₅)2PN(CH₂C₆H₅)CH₂CH₂N(CH₂C₆H₅)P(C₆H₅)2) 
• 940295-88-5 N,N'-ethane-1,2-diylbis[N-benzyl-P,P-diphenyl(phosphinic amide)] 

Relevant academic research and scientific papers

Double dearomatization of bis(diphenviphosphinamides) through anionic cyclization. A facile route of accessing multifunctional systems with antitumor properties

(Chemical Equation Presented) The sequential one-pot double dearomatization of bis(N-benzyl-P,P-diphenylphosphinamides) via anionic cyclization is described for the first time. Protonation and alkylation of the dearomatized dianions provide bis(tetrahydro

New bis(phosphines) derived from N,N′-substituted ethylenediamine derivatives. Synthesis and transition metal chemistry of X2PN(R)CH2CH2(R)NPX2 (R = CH2Ph or Ph, X = Ph; R = CH2Ph, X2 = O2C6H4).

The bis(phosphines) of the type X2PN(R)CH2CH2(R)NPX2 (R = Ph or CH2Ph, X = Ph; R = CH2Ph, X2 = O2C6H4) with the ethylenediamine framework were prepared by reaction of X2PCl with the corresponding N,N′-substituted ethylenediamine derivatives. These ligands readily formed complexes with Group 6 metals and RuII, NiII, PdII and PtII. All complexes were characterised by elemental analysis, IR and NMR spectroscopic methods of which 31P-{1H} is most valuable. The structures of the bis(phosphine) ligand Ph2PN(CH2Ph)CH2CH2(CH 2Ph)NPPh2 and its platinum(II) complex cis-[PtCl2{PPh2N(CH2Ph)CH2CH 2(CH2Ph)NPPh2}] were determined by X-ray crystallography. The ligand crystallises in the extended conformation with both the nitrogen atoms nearly planar and the bond angles around them close to 120°. The P-N distances are shorter than normally accepted P-N single bond lengths (ca. 1.77 A) suggesting some degree of P-N π bonding. The seven-membered chelate ring in the platinum complex is non-planar but the metal atom is in a typical square planar environment with two phosphorus atoms and two chlorine atoms in a mutually cis disposition and the ethylenediamine bridge is folded with respect to the plane in an "open envelope" fashion.

PREPARATION AND 31P NMR STUDIES OF PLATINUM COMPLEXES OF SOME CHIRAL, BIDENTATE PHOSPHINES

Two chiral diphosphines of formula RN(P(C6H5)2)2, S-peap and S-alap, have been prepared from S-α-phenethylamine and the ethyl ester of S-alanine, respectively.Their syntheses, and the preparation of the achiral diphosphine beap, N,N'-bis(diphenylphosphino)-N,N'-dibenzylethylenediamine, are described.Platinum complexes of these bidentate ligands of formula Pt(chelate)CH3Cl and ClO4 (X=acetone; p-YC5H4N, when Y=CH3, C2H5, CHO, CO2CH3, H and N(CH3)2; and a series of monodentate, Group V donor ligands, P(C2H5)3, P(C3H7)3, P(C8H17)3, PCH3(C6H5)2, P(CH3)2C6H5, P(C6H5)3, P(C6H11)(C6H5)2, P(C6H11)2C6H5, P(C6H11)3, P(C6H5)2N(C2H5)2, As(C6H5)3 and Sb(C6H5)3) have been prepared and their 1H and 31P NMR parameters recorded.The cationic pyridine complexes show a correlation of the ρ values of the para substituent to some of the 31P chemical shifts and coupling constants.The steric and electronic properties of the diphosphine ligands have been investigated by comparing their 31P NMR parameters with those of analogous complexes containing (+)-diop and S,S-chiraphos.