81440-45-1Relevant academic research and scientific papers
BENZIMIDAZOLE OR INDOLE AMIDES AS INHIBITORS OF PIN1
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Page/Page column 27, (2010/11/08)
The invention relates to compounds of the formula (1) and to pharmaceutically acceptable salts and solvates thereof, wherein the variables are defined herein. The invention also relates to methods of treating abnormal cell growth in mammals by administering the compounds of formula (1) and to pharmaceutical compositions for treating such disorders that contain the compounds of formula (1). The invention also relates to methods of preparing the compounds of formula (1).
Synthesis of a novel class of heteroaromatic amino acids and their use in the preparation of analogues of luteinizing hormone-releasing hormone
Nestor Jr.,Horner,Ho,Jones,McRae,Vickery
, p. 320 - 325 (2007/10/02)
A novel class of heterocyclic aromatic amino acids based on the 3-(2-benzimidazolyl)alanine system has been generated by chiral synthesis from D- or L-aspartic acid. The use of variously substituted o-phenylenediamines for condensation with the β-carboxyl
