81446-10-8

Upstream product

• 81424-59-1 7-iodo-5-heptynoic acid ethyl ester 
• 81424-22-8 methyl (1R*,2S*,3R*)-2-(dimethoxymethyl)-3-phenyl-5-oxocyclopentanecarboxylate 

Downstream Products

• 81424-31-9 (+/-)-11α-phenyl-11-deoxy-PGE₁ ethyl ester 
• 81424-29-5 (+/-)-11α-phenyl-11-deoxy-PGE₁ ethyl ester 
• 81424-27-3 (+/-)-11α-phenyl-15-dehydro-11-deoxy-PGE₁ ethyl ester 
• 81424-34-2 7-[(1R,2S,3R)-2-((E)-(S)-3-Hydroxy-oct-1-enyl)-5-oxo-3-phenyl-cyclopentyl]-heptanoic acid 
• 81424-32-0 7-[(1R,2S,3R)-2-((E)-3-Hydroxy-oct-1-enyl)-5-oxo-3-phenyl-cyclopentyl]-heptanoic acid 
• 81424-25-1 ethyl 7-<(1R*,2S*,3R*)-2-(dimethoxymethyl)-5-oxo-3-phenylcyclopentyl>heptanoate 
• 81424-26-2 7-((1S,2R,3S)-2-Formyl-5-oxo-3-phenyl-cyclopentyl)-heptanoic acid ethyl ester 
• 81424-24-0 ethyl 7-<(1R*,2S*,3R*)-2-(dimethoxymethyl)-5-oxo-3-phenylcyclopentyl>-5-heptynoate 

Relevant academic research and scientific papers

The Total Synthesis of Prostaglandins by the Tropolone Route

A general synthesis from α-tropolone methyl ether of natural and modified prostaglandins is detailed.A key intermediate in the synthesis, 7-methoxybicyclohepta-3,6-dien-2-one, has been secured from α-tropolone methyl ether in improved yield and con