81453-02-3

Basic information

• Product Name: (1S,2S)-1-Benzyl-2-vinyl-cyclohexanecarbaldehyde
• CAS NO: 81453-02-3
• Molecular Weight: 228.334
• Mol File: 81453-02-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1S,2S)-1-Benzyl-2-vinyl-cyclohexanecarbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,2S)-1-Benzyl-2-vinyl-cyclohexanecarbaldehyde(81453-02-3)
• EPA Substance Registry System: (1S,2S)-1-Benzyl-2-vinyl-cyclohexanecarbaldehyde(81453-02-3)

Safety Data

• Hazardous Substances Data: 81453-02-3(Hazardous Substances Data)

Upstream product

• 1826-67-1 vinyl magnesium bromide 
• 74500-37-1 (S)-2-{[1-Cyclohex-1-enyl-meth-(Z)-ylidene]-amino}-3,3-dimethyl-butyric acid tert-butyl ester 
• 620-05-3 iodomethylbenzene 

Relevant articles and documents

DIASTEREOSELECTIVE AND ENANTIOSELECTIVE SYNTHESIS OF 1,2-DISUBSTITUTED CYCLOALKANECARBOXALDEHYDES

A highly useful method for diastereoselective and enantioselective synthesis of trans- and cis-1,2-disubstituted cycloalkanecarboxaldehydes (trans- and cis-10), useful chiral synthons having asymmetric tertiary and quaternary carbon atoms in vicinal positions in their rings, is devised starting from cycloalkenecarboxaldehydes (5). t-Leucine t-butyl ester (2.R=But), a highly effective chiral auxiliary reagent in the present method, can be recovered for recycling without any loss of optical purity.Some mechanistic explanations on the strereochemical courses of the reactions are presented.