81470-91-9

Upstream product

• 112452-72-9 (2R,4S,5S,6S)-1-(tert-Butyl-diphenyl-silanyloxy)-2,4-dimethyl-6-((4S,5S)-2,2,5-trimethyl-[1,3]dioxan-4-yl)-heptane-3,5-diol 
• 77-76-9 2,2-dimethoxy-propane 
• 112452-72-9 (2R,3S,4S,5S,6S)-1-(tert-Butyl-diphenyl-silanyloxy)-2,4-dimethyl-6-((4S,5S)-2,2,5-trimethyl-[1,3]dioxan-4-yl)-heptane-3,5-diol 
• 112452-72-9 (2R,3R,4S,5S,6S)-1-(tert-Butyl-diphenyl-silanyloxy)-2,4-dimethyl-6-((4S,5S)-2,2,5-trimethyl-[1,3]dioxan-4-yl)-heptane-3,5-diol 
• 81470-90-8 (2S,3S,4R)-4-{(4S,5S,6S)-6-[(R)-2-(tert-Butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-2,2,5-trimethyl-[1,3]dioxan-4-yl}-2-methyl-pentane-1,3-diol 
• 139016-74-3 (2S,3R,4R)-2-((4R,5R)-2,2,5-Trimethyl-[1,3]dioxan-4-yl)-4-((4S,5S)-2,2,5-trimethyl-[1,3]dioxan-4-yl)-pentan-3-ol 
• 139016-69-6 (2R,3R,4S,5S,6R,7S,8S)-5-(tert-Butyl-dimethyl-silanyloxy)-2,4,6,8-tetramethyl-nonane-1,3,7,9-tetraol 
• 139016-77-6 (2S,3S,4R,5R,6S,7R,8R)-9-(tert-Butyl-diphenyl-silanyloxy)-2,4,6,8-tetramethyl-nonane-1,3,5,7-tetraol 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 81470-89-5 [(2R,3R)-3-((S)-1-{(4R,5S,6S)-6-[(R)-2-(tert-Butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-2,2,5-trimethyl-[1,3]dioxan-4-yl}-ethyl)-oxiranyl]-methanol 
• 81470-86-2 (S)-2-{(4R,5S,6S)-6-[(R)-2-(tert-Butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-2,2,5-trimethyl-[1,3]dioxan-4-yl}-propionaldehyde 
• 81470-80-6 {(2S,3S)-3-[(R)-1-((4S,5R)-2,2,5-Trimethyl-[1,3]dioxan-4-yl)-ethyl]-oxiranyl}-methanol 
• 81470-87-3 (E)-(R)-4-{(4S,5R,6S)-6-[(R)-2-(tert-Butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-2,2,5-trimethyl-[1,3]dioxan-4-yl}-pent-2-enoic acid ethyl ester 
• 81479-08-5 2,2-Dimethyl-propionic acid (R)-2-{(4S,5R,6S)-6-[(R)-2-(tert-butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-2,2,5-trimethyl-[1,3]dioxan-4-yl}-propyl ester 

Relevant academic research and scientific papers

Asymmetric Synthesis of C-19 to C-27 Fragment of Rifamycin-S

A highly stereoselective asymmetric synthesis of C-19 to C-27 fragment of Rifamycin-S consisting of 7 contiguous asymmetric centres is described involving Ipc2BH as the chiral hydroborating reagent.

3-METHYL-γ-BUTYROLACTONE AS A SOURCE OF 2-METHYL-3-HYDROXYKETONES AND 2-METHYL-1,3-DIOLS: A SYNTHESIS OF THE C19-C27 FRAGMENT OF RIFAMYCIN S BY LINEAR ITERATION

3-Methyl-γ-butyrolactone has been employed as a source of 2-methyl-3-hydroxyketones after functioning as a template for the preparation of enantiomerically pure propionate chains.This method is exemplified by the preparation of the C19-C27 propionate frag