81480-62-8Relevant articles and documents
Hydrogen-Borrowing Amination of Secondary Alcohols Promoted by a (Cyclopentadienone)iron Complex
Aiolfi, Francesco,Bai, Xishan,Cettolin, Mattia,Dal Corso, Alberto,Gennari, Cesare,Piarulli, Umberto,Pignataro, Luca
, p. 3545 - 3555 (2019/09/09)
Thanks to a highly active catalyst, the scope of the (cyclopentadienone)iron complex-promoted 'hydrogen-borrowing' (HB) amination has been expanded to secondary alcohols, which had previously been reported to react only in the presence of large amounts of co-catalysts. A range of cyclic and acyclic secondary alcohols were reacted with aromatic and aliphatic amines giving fair to excellent yields of the substitution products. The catalyst was also able to promote the cyclization of diols bearing a secondary alcohol group with primary amines to generate saturated N-heterocycles.
One-Pot Synthesis of Substituted Pyrrolidines via Aminomercuration-Demercuration of 1,4- and 1,5-Hexadiene
Barluenga, J.,Najera, C.,Yus, M.
, p. 1297 - 1299 (2007/10/02)
The aminomercuratione-demercuration of 1,4- and 1,5-hexadiene yield cis- and trans-2,5-dimethyl-N-arylpyrrolidines via one-pot process.The intermolecular cyclization reaction goes through the corresponding mercurated pyrrolidines; these intermediates were isolated and characterized when the mercuration reaction was completed.The high stereoselectivity observed allows an easy way of synthesis for N-substituted trans-2,5-dimethylpyrrolidines.
