81482-70-4

Basic information

• Product Name: (R)-3-Acetoxymethyl-7-(tert-butoxycarbonyl-hydrazono)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester
• Synonyms: (R)-3-Acetoxymethyl-7-(tert-butoxycarbonyl-hydrazono)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester
• CAS NO: 81482-70-4
• Molecular Weight: 551.62
• Mol File: 81482-70-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-3-Acetoxymethyl-7-(tert-butoxycarbonyl-hydrazono)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-Acetoxymethyl-7-(tert-butoxycarbonyl-hydrazono)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester(81482-70-4)
• EPA Substance Registry System: (R)-3-Acetoxymethyl-7-(tert-butoxycarbonyl-hydrazono)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester(81482-70-4)

Safety Data

• Hazardous Substances Data: 81482-70-4(Hazardous Substances Data)

Upstream product

• 59128-53-9 benzhydryl 7-oxocephalosporanate 
• 870-46-2 t-butoxycarbonylhydrazine 

Downstream Products

• 82954-47-0 (6R,7R)-3-Acetoxymethyl-7-[N'-tert-butoxycarbonyl-N-(2-thiophen-2-yl-acetyl)-hydrazino]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 81482-80-6 (6R,7R)-3-Acetoxymethyl-7-(N'-tert-butoxycarbonyl-hydrazino)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 

Relevant articles and documents

SYNTHESIS OF 7-HYDRAZINOCEPHALOSPORINS

Hydrazonation of 7-oxocephems 2a,b, followed by borane reduction of the resulting E and Z hydrazono compounds 3a,b and 4a,b, provided the key intermediates 5a,b, which were acylated to 6a,b and then deprotected to yield the 7-hydrazinocephalosporin deriva