81491-29-4

Upstream product

• 81491-52-3 (1R,2S)-2-Formyl-3,3-dimethyl-cyclobutanecarboxylic acid methyl ester 
• 81491-50-1 (1S,2S)-2-Formyl-3,3-dimethyl-cyclobutanecarboxylic acid methyl ester 
• 90107-88-3 (1R,2S)-2-(Benzenesulfonyl-ethoxycarbonyl-methyl)-3,3-dimethyl-cyclobutanecarboxylic acid methyl ester 
• 81491-55-6 (1R,2S)-2-Hydroxymethyl-3,3-dimethyl-cyclobutanecarboxylic acid methyl ester 
• 7605-30-3 ethyl 2-phenylsulfonylacetate 
• 77-78-1 dimethyl sulfate 
• 81491-28-3 (1S,2R)-3,3-Dimethyl-2-phenylsulfanylmethyl-cyclobutanecarboxylic acid methyl ester 

Downstream Products

• 81521-01-9 N-Methyl-2'-<(2-cyanoethyl)thio>-2α-<(E)-6-(benzyloxy)-3-methyl-3-hexenyl>-3,3-dimethylcyclobutane-1β-carboxanilide 
• 81491-36-3 N-Methyl-2'-<(2-cyanoethyl)thio>-2α-<(E)-6-<(methylsulfonyl)oxy>-3-methyl-3-hexenyl>-3,3-dimethylcyclobutane-1β-carboxanilide 
• 81491-34-1 Acetic acid (E)-6-((1R,4S)-4-{[2-(2-cyano-ethylsulfanyl)-phenyl]-methyl-carbamoyl}-2,2-dimethyl-cyclobutyl)-4-methyl-hex-3-enyl ester 
• 81491-35-2 (1R,2S)-2-((E)-6-Hydroxy-3-methyl-hex-3-enyl)-3,3-dimethyl-cyclobutanecarboxylic acid [2-(2-cyano-ethylsulfanyl)-phenyl]-methyl-amide 
• 81491-38-5 (E)-1α,3,4,7,8,9β,10,11-Octahydro-6,10,10-trimethyl-3-<<2-(methylamino)phenyl>sulfinyl>-2H-bicyclo<7.2.0>undecen-2-one 
• 90191-52-9 2α<(E)-6-(Benzyloxy)-3-methyl-3-hexenyl>-3,3-dimethylcyclobutane-1β-carboxylic Acid 
• 81491-31-8 [(1R,2S)-2-((E)-1-Benzenesulfonyl-6-benzyloxy-3-methyl-hex-3-enyl)-3,3-dimethyl-cyclobutylmethoxy]-tert-butyl-dimethyl-silane 
• 90107-93-0 2α<(E)-6-(Benzyloxy)-3-methyl-1-(phenylsulfonyl)-3-hexenyl>-3,3-dimethyl-1β-(hydroxymethyl)cyclobutane 
• 81491-30-7 3,3-Dimethyl-1β-<<(tert-butyldimethylsilyl)oxy>methyl>-2α-<(phenylsulfonyl)methyl>cyclobutane 
• 81491-33-0 2α<(E)-6-(Benzyloxy)-3-methyl-3-hexenyl>-3,3-dimethyl-1β-(hydroxymethyl)cyclobutane 

Relevant academic research and scientific papers

Medium-Ring Ketone Synthesis. Total Syntheses of (+/-)-Isocaryophyllene and (+/-)-Caryophyllene

Total syntheses of (+/-)-isocaryophyllene and (+/-)-caryophyllene are reported.The key step involves a novel construction of the nine-membered ring in these natural products by a base-induced intramolecular acyl transfer reaction of 13-membered lactam sul