81496-30-2

Basic information

• Product Name: (S)-4-FLUORO-3-PHENOXYBENZALDEHYDE-CYANHYDRINE
• Synonyms: (S)-4-FLUORO-3-PHENOXYBENZALDEHYDE-CYANHYDRINE;(S)-4-Fluoro-3-phenoxybenzaldehyde cyanohydrin;(αS)-4-Fluoro-α-hydroxy-3-phenoxybenzeneacetonitrile
• CAS NO: 81496-30-2
• Molecular Formula: C₁₄H₁₀FNO₂
• Molecular Weight: 243.23
• Product Categories: Aromatics;Chiral Reagents;Impurity
• Mol File: 81496-30-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (S)-4-FLUORO-3-PHENOXYBENZALDEHYDE-CYANHYDRINE(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-4-FLUORO-3-PHENOXYBENZALDEHYDE-CYANHYDRINE(81496-30-2)
• EPA Substance Registry System: (S)-4-FLUORO-3-PHENOXYBENZALDEHYDE-CYANHYDRINE(81496-30-2)

Safety Data

• Hazardous Substances Data: 81496-30-2(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 81496-30-2 differently. You can refer to the following data:
1. A decomposition product of Flumethrin. A Flumethrin impurity.
2. (S)-4-Fluoro-3-phenoxybenzaldehyde Cyanhydrine is a decomposition product of Flumethrin. A Flumethrin impurity.

Upstream product

• 143680-40-4 (S)-(+)-1-cyano-1-(4-fluoro-3-phenoxyphenyl)methyl acetate 

Relevant articles and documents

One-Pot Synthesis of Optically Active Cyanohydrin Acetates from Aldehydes via Lipase-Catalyzed Kinetic Resolution Coupled with in Situ Formation and Racemization of Cyanohydrins

A novel one-pot synthesis of optically active cyanohydrin acetates from aldehydes has been accomplished by lipase-catalyzed kinetic resolution coupled with in situ formation and racemization of cyanohydrins in an organic solvent.Racemic cyanohydrins 2, generated from aldehydes 1 and acetone cyanohydrin in diisopropyl ether under the catalysis of basic anion-exchange resin (OH- form), were acetylated stereoselectively by a lipase from Pseudomonas cepacia (Amano) with isopropenyl acetate as an acylating reagent.The (S)-isomer of 2 was preferentially acetylated by the lipase, while the unreacted (R)-isomer was continuously racemized through reversible transhydrocyanation catalyzed by the resin.These processes thus enabled one stage conversion of various aldehydes 1a-n into the corresponding (S)-cyanohydrin acetates 3a-n with up to 94 percent ee in 63-100 percent conversion yields.The racemization of the optically active cyanohydrin 2e by Amberlite IRA-904 (OH- form) was found to be much faster then the enzymatic acetylation, confirming the effective second-order asymmetric transformation.Enzymatic deacetylation of (S)-cyanohydrin acetates in an organic solvent and the synthesis of optically active pyrethroids are also described.

Cyclopropane carboxylates

Esters in their stereoisomeric form or mixtures thereof of the formula STR1 wherein R1 and R are different and individually selected from the group consisting of hydrogen, fluorine and bromine, R2 is selected from the group consisting of --CN and --C CH and R3 is a hydrocarbyl group having pesticidal properties and their preparations.