815-52-1

Basic information

• Product Name: 3-Pentanone, 2-bromo-
• Synonyms: 3-Pentanone, 2-bromo-;2-Bromo-3-pentanone
• CAS NO: 815-52-1
• Molecular Formula: C₅H₉BrO
• Molecular Weight: 165.03
• Mol File: 815-52-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 55°C/15mmHg(lit.)
• Appearance: /
• Density: 1.355±0.06 g/cm3(Predicted)
• Refractive Index: 1.4580 to 1.4620
• CAS DataBase Reference: 3-Pentanone, 2-bromo-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pentanone, 2-bromo-(815-52-1)
• EPA Substance Registry System: 3-Pentanone, 2-bromo-(815-52-1)

Safety Data

• RIDADR: UN 1224 3/PG III
• HazardClass: 3
• PackingGroup: III
• Hazardous Substances Data: 815-52-1(Hazardous Substances Data)

Usage

General Description

3-Pentanone, 2-bromo- is a chemical compound consisting of a five-carbon ketone with a bromine atom attached to the second carbon in the chain. It is often used in organic synthesis and as a reagent in chemical reactions due to its versatile reactivity. The presence of both a ketone and a bromine group in the molecule allows for a wide range of potential reactions and applications in various industries. Its properties and structure make it useful in the production of pharmaceuticals, fragrances, and other specialty chemicals. Additionally, it can be used as an intermediate in the synthesis of other organic compounds. Despite its reactivity, proper handling and regulatory guidelines should be followed to ensure safe use and disposal.

Upstream product

• 1629-58-9 4-penten-3-one 
• 584-02-1 2-pentanol 

Downstream Products

• 52414-89-8 2,4-Diaethyl-5-methyl-thiazol 
• 52414-91-2 4-ethyl-5-methyl-thiazole 
• 56157-57-4 4-ethyl-5-methyl-2-phenyl-thiazole 
• 740021-16-3 2-(4,4'-dimethoxy-benzhydryl)-4-ethyl-5-methyl-thiazole 
• 102670-64-4 4-Amino-5-chloro-2-(pentan-3-on-2-yl)oxy-N-(2-diethylaminoethyl)benzamide hydrochloride 
• 96-22-0 pentan-3-one 
• 96428-74-9 2-ethyl-3-methyl-8-phenylmethoxyimidazo[1,2-a]pyridine 
• 55848-19-6 1-hydroxy-2-methyl-1-phenyl-pentan-3-one 
• 55848-19-6 1-Hydroxy-2-methyl-1-phenyl-pentan-3-one 
• 55848-19-6 1-hydroxy-2-methyl-1-phenylpentan-3-one 
• 32272-57-4 2,5-Dimethyl-4-ethylthiazol 
• 17042-24-9 2-mercapto-pentan-3-one 
• 321307-10-2 (±)-(E,E)-1,6-diphenylhexa-1,5-diene-3,4-diol 
• 58547-32-3 syn-5-hydroxy-4-methyl-7-phenyl-3-heptanone 

Relevant articles and documents

A H2O2/HBr system-several directions but one choice: oxidation-bromination of secondary alcohols into mono- or dibromo ketones

In this work we found that a H2O2-HBr(aq) system allows synthesis of α-monobromo ketones and α,α′-dibromo ketones from aliphatic and secondary benzylic alcohols with yields up to 91%. It is possible to selectively direct the process toward the formation of mono- or dibromo ketones by varying the amount of hydrogen peroxide and hydrobromic acid. The convenience of application, simple equipment, multifaceted reactivity, and compliance with green chemistry principles make the application of the H2O2-HBr(aq) system very attractive in laboratories and industry. The proposed oxidation-bromination process is selective in spite of known properties of ketones to be oxidized by the Baeyer-Villiger reaction or peroxidated with the formation of compounds with the O-O moiety in the presence of hydrogen peroxide and Bronsted acids.

Oxidation of primary and secondary alkanols with the CeIII-LiBr- H2O2 system

Action of a novel oxidation system, Ce(NO3)3? 6H2O (cat.)-LiBr (cat.)-H2O2 (stoichiometric oxidant) on primary aliphatic C6-C9 alcohols gives selectively esters, whereas secondary aliphatic C5-C9 alcohols are converted into ketones. Selectivity of these transformations is provided by slow addition of H2O2 to the other reactants.