81509-19-5

Upstream product

• 59259-41-5 acide p-nitro-phenyl-3 endo bicyclo<2.2.1> heptene-5 carboxylique-2 endo 
• 882-06-4 4-nitro-trans-cinnamic acid 
• 14290-91-6 (Z)-3-(4-nitrophenyl)acrylic acid 
• 59259-41-5 3-endo-(p-nitrophenyl)bicyclo[2.2.1]hept-5-ene-2-exo-carboxylic acid 
• 186581-53-3 diazomethane 

Downstream Products

• 59259-41-5 3-endo-(p-nitrophenyl)bicyclo[2.2.1]hept-5-ene-2-exo-carboxylic acid 
• 59259-41-5 acide p-nitro-phenyl-3 exo bicyclo<2.2.1>heptene-5 carboxylique-2 endo 

Relevant academic research and scientific papers

Enzymatic kinetic resolution of aromatic substituted norbornene mono-esters using pig's liver esterase

Pig's liver esterase (PLE) has been used as a chiral catalyst in the enzymatic kinetic resolution of aromatic substituted norbornene mono-esters, methyl 3-endo-phenylbicyclo[2.2.1]hept-5-ene-2-exo-carboxylate and its endo-counterpart, methyl 3-endo-p-nitro-phenyl-bicyclo[2.2.1]hept-5-ene-2-exo-carboxylate and methyl 3-endo-benzoylbicyclo[2.2.1]hept-5-ene-2-exo-carboxylate. In this study a range of low to high enantioselectivities (83% ee) was observed. The effect of co-solvents has also been examined.