81535-91-3Relevant academic research and scientific papers
Calixarenes. 7. p-Phenycalixarene
Gutsche, C. David,No, Kwang Hyun
, p. 2708 - 2712 (2007/10/02)
p-Phenylcalixarene (11), in the cone conformation, is a basket-shaped compound containing a large cavity and, therefore, is of interest for studies of host-guest complexation.Its unequivocal synthesis has been achieved by the stepwise method of Hayes and Hunter, by starting with 2-bromo-4-phenylphenol and adding methylene and p-phenylphenol groups sequentially until a linear tetramer (9) is attained.Removal of the bromine followed by acid-catalyzed cyclization yields the calixarene 11, along with two other materials that are presumed to be the isomeric macrocyclic compounds 12 and 13. p-Phenylcalixarene synthesized in this fashion is different from the compound reported by Zinke from the condensation of p-phenylphenol and formaldehyde in the presence of base, and it appears that 11 is not a major product, and perhaps not even a minor product, of that reaction mixture.
Calixarenes. 8. Short, Stepwise Synthesis of p-Phenylcalixarene, p-Phenyl-p-tert-butylcalixarene, and Derived Products
No, Kwang Hyun,Gutsche, C. David
, p. 2713 - 2719 (2007/10/02)
Calixarenes (Schemes I-IV) have been previously obtained by a one-flask process (Zinke synthesis) and by a multistep process (Hayes and Hunter synthesis).The former has the advantage of speed and simplicity but the disadvantage of difficult-to-separate pr
