81555-96-6

Basic information

• Product Name: 1-{[5-(4-pyridinyl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetone
• Synonyms: 1-{[5-(4-pyridinyl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetone
• CAS NO: 81555-96-6
• Molecular Formula: C10H9N3O2S
• Molecular Weight: 235.26236
• Mol File: 81555-96-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-{[5-(4-pyridinyl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-{[5-(4-pyridinyl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetone(81555-96-6)
• EPA Substance Registry System: 1-{[5-(4-pyridinyl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetone(81555-96-6)

Safety Data

• Hazardous Substances Data: 81555-96-6(Hazardous Substances Data)

Upstream product

• 78-95-5 chloroacetone 
• 15264-63-8 5-(4-pyridinyl)-1,3,4-oxadiazole-2-thiol 

Relevant articles and documents

Ring Transformation of 1,3,4-Oxadiazole to s-Triazole-Fused Heterocycles. New Synthetic Route for Thiazolo-s-triazole and 7H-s-Triazolothiadiazine

s-Triazole-fused heterocycles have been synthesized by an intramolecular transformation of some 1,3,4-oxadiazole ketones with ammonia or hydrazine.The α- ketone 2m gave thiazolo-s-triazole (4m), accompanied by a small amount of the hydrazide 9m on treatment with ammonium acetate in acetic acid.Similar treatment of ketones 2a and 2b afforded only the hydrazides 9a and 9b, respectively.Ketones 2a-n reacted with hydrazine hydrate in acetic acid to give 7H-s-triazolothiadiazines 5a-n.However, ketones 2o-q, with substituents α to the carbonyl group, could not be converted to the corresponding fused-ring systems.Mechanisms for these transformations are proposed.