815576-26-2Relevant academic research and scientific papers
SILICON COMPOUNDS AND THEIR USE
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Page/Page column 15, (2008/06/13)
A compound of formula (1): wherein A is -CH2CH2-, -CH=CH- or -C=-C-; B is aryl or heteroaryl; D is optionally present and is -C(O)-, -C(O)NH-, -C(O)CH2- or -C(O)CH2- O-; E is optionally present and is alkylene or heteroarylene; R1 is hydrogen or alkyl; R2 is hydrogen, alkyl, aryl, cycloalkyl, heteroaryl or heterocycloalkyl; R3 and R4 are the same or different and are each hydrogen, alkyl or cycloalkyl; and each R5 is the same or different and is alkyl, -alkyl-aryl or -alkyl-cycloalkyl, or R5-Si-R5 taken together form heterocycloalkyl; or a pharmaceutically acceptable salt thereof.
SILICON-COMPRISING AMINOTHIAZOLE DERIVATIVES AS CDK INHIBITORS
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, (2010/02/10)
A compound of formula (I), wherein R1 and R2 are the same or different and are each hydrogen, halogen or alkyl; R3 is aryl or heteroaryl, either of which is substituted at least once with -Si(R7)3, an
