815576-68-2 Usage
Uses
Different sources of media describe the Uses of 815576-68-2 differently. You can refer to the following data:
1. Quinolactacin A1 is the dominant analogue of a family of quniolone metabolites produced by Penicillium citrinum. Quinolactacin A1 rapidly epimerises to equilibrate with its diastereomer quinolactacin A2 in protic solvents. The mixture has been shown to inhibit acetylcholinesterase and TNF production.
2. Quinolactacin A1 is the dominant analogue of a family of quinolone metabolites produced by Penicillium citrinum. Quinolactacin A1 rapidly epimerises to equilibrate with its diastereomer quinolactacin A2 in protic solvents. The mixture has been shown to inhibit acetylcholinesterase and TNF production.
3. Quinolactacin A1 is an inhibitor of AChE (acetylcholinesterase) and TNF production.
Check Digit Verification of cas no
The CAS Registry Mumber 815576-68-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,1,5,5,7 and 6 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 815576-68:
(8*8)+(7*1)+(6*5)+(5*5)+(4*7)+(3*6)+(2*6)+(1*8)=192
192 % 10 = 2
So 815576-68-2 is a valid CAS Registry Number.
815576-68-2Relevant articles and documents
Engineered Biosynthesis of Fungal 4-Quinolone Natural Products
Liu, Mengting,Ohashi, Masao,Tang, Yi
supporting information, p. 6637 - 6641 (2020/09/02)
Quinolone-containing natural products are widely found in bacteria, fungi, and plants. The fungal quinolactacins, which are N-methyl-4-quinolones, display a wide spectrum of biological activities. Here we uncovered a concise nonribosomal peptide synthetase pathway involved in quinolactacin A biosynthesis from Penicillium by using heterologous reconstitution and in vitro enzymatic synthesis. The N-desmethyl analog of quinolactacin A was accessed through the construction of a hybrid bacterial and fungi pathway in the heterologous host.
Concise enantioselective syntheses of quinolactacins A and B through alternative winterfeldt oxidation
Zhang, Xuqing,Jiang, Weiqin,Sui, Zhihua
, p. 4523 - 4526 (2007/10/03)
Enantioselective total syntheses of (+)-quinolactacin B and (+)-quinolactacin A2 through asymmetric Pictet-Spengler cyclization and KO2 oxidation-an alternative Winterfeldt condition-are described.
