81559-75-3Relevant academic research and scientific papers
A Reinvestigation of the Cyclodesulfurization of Thiosemicarbazides
Sunder, Shyam,Peet, Norton P.,Barbuch, Robert J.
, p. 1601 - 1604 (2007/10/02)
A recent report describing the preparation of 2-(substituted-amino)-3,4-dihydro-5H-1,3,4-benzotriazepin-5-ones (3), by the cyclodesulfurization of hydrazides prepared from o-aminobenzoylhydrazine (1) and isothiocyanates, is erroneous.The products resulting from this reaction sequence are, instead 2-(substituted-amino)-5-(o-aminophenyl)-1,3,4-oxadiazoles (4).Alternate synthesis of the oxadiazoles led to the correct structural assignments.
